Present report relates to duplication of ascending colon with cyst formation along with ectopia of gastric glands in lamina propria of colon. Heterotopia or ectopia is defined as presence of an organ outside its normal anatomic site. Ileum is the commonest site of heterotopia in gastrointestinal tract. Rarely, heterotopia may involve ascending colon. In the present case, cyst wall also had a thickened area, measuring 1×1×0.5 cm, consisting of hypertrophic muscularis. Cyst wall showed ulceration in continuity with colonic columnar epithelium. In addition, lamina propria also showed mixed leucocytic infiltration. The lesion was finally diagnosed as duplication of ascending colon with cyst formation and heterotopia of benign gastric glands, hemorrhage and ulceration. Keywords: Large intestinal cyst with two corresponding parts, ectopia of gastric glands with ulceration and haemorrhage.