Undifferentiated pleomorphic sarcoma of the pancreas with novel SARM1‐NTRK1 gene fusion and associated pancreatitis, panniculitis, and polyarthritis syndrome

Abstract

LETTER TO THE EDITOR 3 of 3 F I G U R E 2 A, Schematic representation of the predicted SARM1-NTRK1 chimeric protein. ARM, Armadillo repeat domain; SAM, Sterile alpha motif; TIR, Toll/interleukin-1. B, Genomic structure depicting the location and orientation of the SARM1 and NTRK1 genes, and the retained exons in fusion transcripts receptor/resistance protein domain; SP, signal peptide; LRR, leucine-rich domain; IgC, immunoglobulin-like domain; TM, transmembrane domain; TK, tyrosine kinase domain.