Une hypercalcémie d'origine double: association myélome et adénome parathyroïdien ectopique

Fery-Blanco, C.; Prati, Clément; Ornetti, Paul; Bevalot, J.; Streit, Gérald; Toussirot, Éric; Wendling, Daniel

doi:10.1016/j.revmed.2007.02.007

Cited by 5 publications

(1 citation statement)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this patient, elevated preoperative serum parathyroid hormone was consistent with hypercalcemia secondary to parathyroid adenoma, however, postoperative serum calcium levels remained above the normal range following normalization of parathyroid hormone levels. Hypercalcemia in patients with concurrent myeloma and parathyroid adenoma has been well-reported [21][22][23]. Additionally, recurrent or persistently elevated calcium following parathyroidectomy has occasionally lead to a new diagnosis of myeloma [24,25].…”

Section: Discussionmentioning

confidence: 99%

A Herald of Plasma Cell Myeloma: A Report of Malignant Plasma Cells Identified in Parathyroid Adenoma and a Review of Non-parathyroid Malignancies in Parathyroid Glands

Cracolici

Grogan

Sukhanova

et al. 2017

Head and Neck Pathol

View full text Add to dashboard Cite

Involvement of the parathyroid glands by non-parathyroid neoplasia is an infrequent event. Rare cases of metastases to the parathyroid gland have been reported in parathyroidectomies and autopsies of patients with known solid or hematopoietic malignancies. Here, we present a case of atypical clonal plasma cells incidentally identified within a parathyroid adenoma resected for hyperparathyroidism and hypercalcemia, which served as the sentinel event for a subsequent diagnosis of plasma cell myeloma. To our knowledge, this is the only reported case of a hematopoietic malignancy involving a parathyroid adenoma and the only reported case of malignant hematopoietic cells initially detected in parathyroidectomy.

show abstract

Section: Discussionmentioning

confidence: 99%

A Herald of Plasma Cell Myeloma: A Report of Malignant Plasma Cells Identified in Parathyroid Adenoma and a Review of Non-parathyroid Malignancies in Parathyroid Glands

Cracolici

Grogan

Sukhanova

et al. 2017

Head and Neck Pathol

View full text Add to dashboard Cite

show abstract

Primary hyperparathyroidism and multiple myeloma complicated by Fanconi syndrome: A fortuitous association?

et al. 2015

View full text Add to dashboard Cite

The forgotten electrolyte, when hypercalcaemia manifest as gait instability and altered mental status

Ugalde¹,

Segura

Oneto

et al. 2018

BMJ Case Reports

View full text Add to dashboard Cite

An altered mental status presents a diagnostic challenge for many clinicians. Described here is a case of primary hyperparathyroidism not initially suspected until after a thorough neurological and infectious cause were excluded. A 60-year-old woman presented with altered mental status and gait instability. Her family noticed progressive gait instability and mood swings for the past 4 months. Initial imaging and laboratory values were unable to explain her symptoms. On transfer out of the intensive care unit, her corrected calcium was found to be 13.3 mg/dL with an elevated parathyroid hormone. Her hypercalcaemia was refractory to medical management. Ultrasound found a 2 cm nodule, which was surgically removed and found to be a parathyroid adenoma. Her calcium normalised and neurological deficits subsided. Hypercalcaemia can lead to a constellation of symptoms that include the classical 'stones, bones, abdominal moans and psychic groans' and electrolyte derangements should be considered in the differential of altered mental status.

show abstract

Une hypercalcémie d'origine double: association myélome et adénome parathyroïdien ectopique

Cited by 5 publications

References 11 publications

A Herald of Plasma Cell Myeloma: A Report of Malignant Plasma Cells Identified in Parathyroid Adenoma and a Review of Non-parathyroid Malignancies in Parathyroid Glands

A Herald of Plasma Cell Myeloma: A Report of Malignant Plasma Cells Identified in Parathyroid Adenoma and a Review of Non-parathyroid Malignancies in Parathyroid Glands

Primary hyperparathyroidism and multiple myeloma complicated by Fanconi syndrome: A fortuitous association?

The forgotten electrolyte, when hypercalcaemia manifest as gait instability and altered mental status

Contact Info

Product

Resources

About