Une longue survie après traitement d’un carcinome épidermoïde de la vésicule biliaire

Bourmèche, M.; Salah, H. Ben; Kallel, M.; Beyrouti, Mohamed Issam; Makni, Saadia; Boudawara, T.; Frikha, M.; Daoud, J.

doi:10.1016/j.canrad.2012.12.005

Cited by 10 publications

(6 citation statements)

References 13 publications

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“…Postoperative adjuvant chemotherapy and radiotherapy have been tried in few cases. Bourmeche, et al reported the use of 45 Gy, combined with 5 fluorouracil and cisplatin chemotherapy, with complete remission [ 10 ]. Based on the current literature and review of few cases of pure SCC of GB, postoperative chemotherapy and radiotherapy could be the best therapeutic option.…”

Section: Discussionmentioning

confidence: 99%

Pure Squamous Cell Carcinoma of the Gallbladder Masquerading as a Hepatic Mass

Perisetti¹,

Raghavapuram²,

Tharian³

et al. 2018

Cureus

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Gallbladder (GB) carcinomas are adenocarcinomas (AC) in the majority of cases. Adenosquamous carcinoma (ASC) and pure squamous cell carcinoma (SCC) of the gallbladder are rarely encountered and comprise 1-3% of gallbladder cancer cases. Pure squamous cell carcinoma of the gallbladder is rarer with less than 1% of the incidence. Most of the published literature is based on case reports and case series. The survival rates of ASC and SCC of the gallbladder are significantly lower (mean of five months) compared to the AC of the gallbladder (mean survival of 11.4 months). Most of these lesions are advanced at presentation, rendering them unresectable and resulting in a poor prognosis. However, if the lesions are diagnosed at an early stage, they could potentially be resectable. We report one such rare case of pure SCC GB presenting as a hepatic mass. The patient subsequently underwent resection of the gallbladder and liver mass with complete recovery and is currently planned for chemotherapy and radiation treatment.

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Section: Discussionmentioning

confidence: 99%

Pure Squamous Cell Carcinoma of the Gallbladder Masquerading as a Hepatic Mass

Perisetti¹,

Raghavapuram²,

Tharian³

et al. 2018

Cureus

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“…In most cases, adjuvant radiotherapy with or without concomitant chemotherapy was used [1,6,9,[20][21][22]. The number of reported cases, the heterogeneity of treatment administered and the limited follow-up for most patients do not allow to draw any conclusion.…”

Section: Discussionmentioning

confidence: 99%

“…For gallbladder adenocarcinoma, complete surgery with R0 resection is the cornerstone of therapy and the recommended treatment is surgical resection with cholecystectomy, liver resection block and lymphadenectomy with or without removal of the biliary tract [9,10]. Several authors have proposed an adjuvant treatment including radiation therapy with or without concomitant chemotherapy with 5-fluorouracil and leucovorin [9,11].…”

Section: Introductionmentioning

confidence: 99%

“…None prospective study has been conducted in patients with squamous-cell carcinoma of gallbladder and data reported in the literature are limited. Only few therapeutic data have been reported from cases report or small series [1,2,7,9,11,15,16].…”

Section: Introductionmentioning

confidence: 99%

“…Several authors have proposed an adjuvant treatment including radiation therapy with or without concomitant chemotherapy with 5-fluorouracil and leucovorin [9,11]. Nevertheless, the benefit of radiotherapy or concomitant chemoradiotherapy after surgery remains controversial.…”

Section: Introductionmentioning

confidence: 99%

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Squamous-Cell Gallbladder Carcinoma: How to Treat?

Verlicchi¹,

Hannoun²,

Bachet³

2015

J Cell Sci Ther

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Squamous-cell gallbladder carcinoma is a very rare cancer with very few therapeutic data available in the literature. We describe a case of this rare disease with a good response under Gemcitabine and Cisplatin after several previous lines of chemotherapy, in an 80-year-old man. In our case, the disease was resistant to FOLFOX, FOLFIRI and Paclitaxel but an impressive partial response was shown after 9 cycles of Gemcitabine and Cisplatin in fourth-line of chemotherapy. Unfortunately, a progression occurred after 12 cycles (7 months). With the intent of finding a new therapeutic option a molecular analysis was performed using Next-Generation Sequencing and two mutations of ERBB2 and PTEN were found. A standard regimen of chemotherapy for squamous-cell gallbladder cancer does not exist and, because of the rarity of this type of cancer, therapeutic trials will probably never be conducted. The end point of this works is to describe this interesting case and make a review of the literature about treatments used for squamous-cell carcinoma of the gallbladder.

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Variants of Gallbladder Carcinoma

Zimmermann¹

2016

Tumors and Tumor-Like Lesions of the Hepatobiliary Tract

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Une longue survie après traitement d’un carcinome épidermoïde de la vésicule biliaire

Cited by 10 publications

References 13 publications

Pure Squamous Cell Carcinoma of the Gallbladder Masquerading as a Hepatic Mass

Pure Squamous Cell Carcinoma of the Gallbladder Masquerading as a Hepatic Mass

Squamous-Cell Gallbladder Carcinoma: How to Treat?

Variants of Gallbladder Carcinoma

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