Une tumeur rétropéritonéale inhabituelle

Primary Solitary Fibrous Tumor of the Retroperitoneum

“…Increased mitotic activity, cellularity, nuclear pleomorphism and the presence of lesional necrosis are ominous features and suggest an increased risk of local recurrence and metastasis. 1 , 2 , 6 None of these elements was observed in our case.…”

“…Anti CD34 antibody is a sensible marker (95% of SFT) but unspecific. 2 , 5 , 6 Anti-CD99 antibody is positive in 70% of the cases. Anti- EMA, antibcl2, and anti-smooth muscle actin antibodies are positive only in 20–35% of the cases.…”

“…1,2 , 4–6 Although the distinction is problematical with histology based examinations alone, sarcomas show cytologic features of malignancy, which are uncommon in SFT. Yet, some characteristics of SFT, such as short oval-spindled nuclei with bland chromatin, are occasionally found in synovial sarcoma, nerve sheath tumors, smooth muscle tumors, and desmoid tumors.…”

“… 1 , 2 , 5 , 6 SFT, synonymously referred to in the past as fibrous mesothelioma, localized fibrous mesothelioma, localized fibrous tumor, localized mesothelioma, pleural fibroma, solitary fibrous mesothelioma and submesothelial fibroma was for a long time considered to be exclusively pleural-based. 1 , 2 , 6 , 7 Now, it has been reported in a wide variety of extrapleural sites including orbit, upper respiratory tract, salivary glands, thyroid, peritoneum, livery, retroperitoneum and pelvis, adrenal gland, kidney, spermafic cord, urinary bladder, prostate, uterine cervix, spinal cord, periosteum, and soft tissue. 5 Retroperitoneum is a rare location.…”

“…Anti- EMA, antibcl2, and anti-smooth muscle actin antibodies are positive only in 20–35% of the cases. 2 , 6 …”