Unfolding the outcomes of surgical treatment of lumbar spinal stenosis—a prospective 5- and 10-year follow-up study

Abstract

Purpose In this prospective study, we aim to determine surgical outcomes in patients with lumbar spinal stenosis (LSS) 10 years after surgery. Methods The study population consisted of 96 LSS patients who underwent decompressive surgery, 72 of whom participated in the 10-year follow-up. The patients completed a questionnaire preoperatively and 3 months, 5 years, and 10 years postoperatively. Outcome measures were satisfaction with the surgical outcomes, the Oswestry Disability Index (ODI), the visual analog scale (VAS), the numeric rating scale (NRS-11), and walking ability quantified in meters. Postoperative improvements at 5 and 10 years were analyzed using linear mixed models. Furthermore, comparisons between postoperative time points were made for clinical courses of pain, disability, and walking ability. Results At the 10-year follow-up, 68% of the patients were satisfied with the surgical outcomes. All the measured outcomes showed statistically significant improvement from baseline to the 5- and 10-year follow-up. The mean VAS score was 9.8 mm higher at the 5-year follow-up and 7.8 mm at the 10-year follow-up compared to the 3-month follow-up point. Similarly, the mean ODI was 4.8% higher at the 10-year follow-up compared to the 3-month follow-up point. Conclusion This study reports the clinical course of pain, disability, and walking distance after LSS surgery with the 10-year follow-up. Based on our study results, patients with LSS could expect to have positive effects of their back surgery up to 10 years. However, minor worsening in pain and disability may occur and one-fourth of the patients may need a reoperation during the 10-year follow-up period.

Long term postoperative results and quality of life after surgery for lumbar spinal stenosis in sub-sahara African countries, the case of Cameroon: A cross-sectional study

“… 20 The significant improvement five years later corroborates a 10-year cohort in Finland. 17 The latter also revealed that quality of life outcomes were not significantly different at five and ten years since the first surgery. This complements previous literature.…”

“… 11 , 12 Many studies abroad have evaluated the quality of life of patients after surgery for LSS both in short (1 year) and long term (5 years and above). 6 , 7 , 13 , 14 , 15 , 16 , 17 In Africa, a plethora of studies have evaluated the epidemiological, clinical and therapeutic aspects of LSS. 9 , 18 , 19 , 20 , 21 Studies conducted in Cameroon and others sub Saharan African countries showed that LSS affects a younger population (40–60 years) compared to Western countries (65–70 years) and thus, incapacitates people who are still in the working population.…”

Long-Term Outcomes after Selective Microendoscopic Laminotomy for Multilevel Lumbar Spinal Stenosis with and without Remaining Radiographic Stenosis: A 10-Year Follow-Up Study

“…lumbar decompression surgery have been reported previously for comparative purposes. 16),19) Specifically, studies have reported a 40-55% JOA recovery rate 10 years after surgery, 11), [19][20][21][22][23][24] lumbar VASs of 30-35 mm, [19][20][21][22] ODIs of 25%-35%, and mean patient satisfaction of 7.0-8.0 points [20][21] following conventional lumbar decompression.…”

Integrative analysis of multi-omics data for discovery of ferroptosis-related gene signature predicting immune activity in neuroblastoma

“…We used either Pearson’s r correlation or Spearman’s rank-order correlation to measure the correlation between two continuous variables. The 3-, 5-, and 10-year prognosis were taken as follow-up nodes ( Hassanzadeh et al, 2017 ; Tuomainen et al, 2020 ; Berberi, 2021 ). The comparison of a continuous variable in two or more than two groups was made using either a parametric test (Student’s t -test or analysis of variance) or non-parametric test (Wilcoxon rank-sum test or Kruskal–Wallis test) if the variable was normally distributed.…”