Unidirectional porous β-tricalcium phosphate induces bony fusion in lateral lumbar interbody fusion

Kumagai, Hiroshi; Abe, Tetsuya; Koda, Masao; Nagashima, Katsuya; Miura, Kousei; Mataki, Kentaro; Fujii, Kengo; Noguchi, Hiroshi; Funayama, Toru; Yamazaki, Masashi

doi:10.1016/j.jocn.2018.09.004

Cited by 15 publications

(16 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…UDPTCP also provided good clinical potential as a bone substitute to fill gaps after the treatment of benign bone tumors of the hand and vertebral fractures 18 . Additionally, in an image-based assessment of lateral interbody fusion in the lumbar spine, UDPTCP was not inferior to the autologous bone graft 19 . In this study, we focused only on bone remodeling, but clinical outcomes should also be evaluated in the future.…”

Section: Discussionmentioning

confidence: 84%

A radiological study of bone remodeling with two different types of porous β-tricalcium phosphate in humans

Kikuchi

Yoshioka

Arai

et al. 2020

Sci Rep

Self Cite

View full text Add to dashboard Cite

In this study we compared the bone remodeling of unidirectional (UDPTCP) and spherical porous β-tricalcium phosphate (SPTCP) radiologically in humans. We performed a retrospective analysis of the data of 14 patients (sex, nine men and five women; age, 37–70 years) who underwent medial opening-wedge high tibial osteotomy (MOWHTO) and were followed up for 12 months after surgery. Two wedge-shaped β-TCPs (one UDPTCP and one SPTCP) were cut and placed parallel to each other in the gap. In Group A (eight knees), UDPTCP was implanted anteriorly and SPTCP posteriorly, while in Group B (six knees), SPTCP was implanted anteriorly and UDPTCP posteriorly. Computed tomography (CT) was performed at 1 week, 6 months, and 12 months after surgery, with the CT attenuation values calculated for UDPTCP and SPTCP. In Groups A and B, the CT attenuation values for UDPTCP were significantly lower at 6 and 12 months after surgery compared to those at 1 week (P < 0.05); nevertheless, no statistical difference in the comparison with SPTCP was observed. After a short-term follow-up of 12 months following MOWHTO, UDPTCP provided earlier bone remodeling than SPTCP. This outcome was achieved regardless of the position, anterior or posterior, in the MOWHTO gap.

show abstract

Section: Discussionmentioning

confidence: 84%

A radiological study of bone remodeling with two different types of porous β-tricalcium phosphate in humans

Kikuchi

Yoshioka

Arai

et al. 2020

Sci Rep

Self Cite

View full text Add to dashboard Cite

show abstract

“…Affinos is also expected to present balanced absorption and regeneration similar to autologous bone from an early stage in clinical applications. However, limited clinical application studies have been reported so far [7][8][9][10][11][12][13]. Here, we report the benefits of Affinos as an absorbable material for bone regeneration by introducing clinical application cases in various fields of orthopedic surgery.…”

Section: Figure 2: An Implant Experiments In a Beagle Model Of A Partimentioning

confidence: 96%

A Novel Unidirectional Porous β-tricalcium Phosphate Bone Substitute in Orthopedic Surgery: A Technical Note and Case Illustrations

Funayama

Noguchi

Kumagai

et al. 2020

Cureus

Self Cite

View full text Add to dashboard Cite

Bone grafting is frequently performed in orthopedic surgeries. Artificial bone is a common grafting material. We have developed an absorbable material for bone regeneration with a unique structure: unidirectional porous β-tricalcium phosphate (Affinos ; Kuraray Co., Ltd., Tokyo, Japan). The most distinctive feature of this material is the ease with which blood can rapidly reach its depths by capillary action due to the unidirectional porous structure. It is also characterized by the presence of micropores, which are known to be beneficial for osteoconductivity both on the surface and inside the material. Favorable artificial bone absorption and regeneration with natural bone were observed in cases of clinical bone graft applications in the spine, extremities, benign bone tumor, trauma, and donor sites. Affinos is useful as a novel absorbable material for bone regeneration in various orthopedic surgeries.

show abstract

“…Use of UDPTCP in calcaneal fracture, benign bone tumors of the hand, lumbar interbody fusion, and early bone remodeling has been reported [7][8][9] , but there is no report of UDPTCP use in OWHTO. We used UDPTCP and SPTCP in OWHTO with stable clinical results, and reported the radiological and clinical results of four cases.…”

Section: Introductionmentioning

confidence: 99%

Use of unidirectional and spherical porous β-tricalcium phosphate in opening-wedge high tibial osteotomy: a case series

et al. 2021

Self Cite

View full text Add to dashboard Cite

Unidirectional porous β-tricalcium phosphate induces bony fusion in lateral lumbar interbody fusion

Cited by 15 publications

References 12 publications

A radiological study of bone remodeling with two different types of porous β-tricalcium phosphate in humans

A radiological study of bone remodeling with two different types of porous β-tricalcium phosphate in humans

A Novel Unidirectional Porous β-tricalcium Phosphate Bone Substitute in Orthopedic Surgery: A Technical Note and Case Illustrations

Use of unidirectional and spherical porous β-tricalcium phosphate in opening-wedge high tibial osteotomy: a case series

Contact Info

Product

Resources

About