In this study, we form integral formulas for Saigo’s hypergeometric integral operator involving V-function. Corresponding assertions for the classical Riemann–Liouville (R-L) and Erdélyi–Kober (E-K) fractional integral operator are extrapolated. Also, by putting in the transformations of Beta and Laplace, we can establish their composition formulas. By selecting the appropriate parameter values, the V-function may be reduced to a variety of functions, including the exponential function, Mittag–Leffler, Lommel, Struve, Wright’s generalized Bessel function, and Bessel and generalized hypergeometric function.