Uniform molecularly imprinted microspheres and nanoparticles prepared by precipitation polymerization: The control of particle size suitable for different analytical applications

Recent advances in molecular imprinting technology: current status, challenges and highlighted applications

“…By changing the ratio of TRIM to DVB, the particle size of the racemic propranolol imprinted polymer beads altered in the range of 130 nm to 2.4 mm. 107 In addition, polymerization temperature has a profound impact on the particle size. For poly(MAA-co-TRIM) particles prepared by PP, when the polymerization temperature was increased from 4 to 83 1C, the particle diameter decreased from several micrometres to several nanometres.…”

“…46 Table 1 summarizes MIPs synthesized by PP. 8,46,84,[95][96][97][98][99][100][101][102][103][104][105][106][107][108][109][110][111] To satisfy different application purposes, MIPs with well controlled physical conformations in different size ranges are highly desirable. Many attempts have been made to evaluate the effect of factors upon sizes and shapes of the obtained particles during PP.…”

Molecularly imprinted nanoparticles based potentiometric sensor with a nanomolar detection limit

“…The triclosan MIP nanobeads were synthesized by the precipitation method as described elsewhere [28,29]. Briefly, the template triclosan (1.0 mmol), AA (2.5 mmol), MMA (4.0 mmol), DVB (60 L), TRIM (320 L) and free-radical initiator AIBN (0.5 mmol) were dissolved in acetonitrile (40 mL) in a 50 mL flask and sonicated for 10 min to maintain homogeneity.…”

Potentiometric Sensor Based on Molecularly Imprinted Polymers for Rapid Determination of Clenbuterol in Pig Urine

“…The clenbuterol MIP beads were synthesized by the precipitation method as described elsewhere [9] . The synthesis processes are as follows: the template clenbuterol (0.4 mmol), functional monomers MAA (2.5 mmol) and MMA (0.83 mmol), cross-linkers DVB 80 (0.4 mmol) and TRIM (1.0 mmol) and free-radical initiator AIBN (0.5 mmol) were dissolved in 40 mL of methanol in a 45-mL flask and sonicated for 10 min to maintain homogeneity.…”