Unihemispheric evidence accumulation in pigeons.

Wittek, Neslihan; Matsui, Hiroshi; Behroozi, Mehdi; Otto, Tobias; Wittek, Kevin; Sarı, Nurullah; Stoecker, Sven; Letzner, Sara; Choudhary, Vikash; Peterburs, Jutta; Güntürkün, Onur

doi:10.1037/xan0000290

Cited by 5 publications

(4 citation statements)

References 95 publications

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“…In the mammalian hippocampal circuit, the majority of input is from the ipsilateral hemisphere, though there are some contralateral projections (Goldowitz et al, 1975; Swanson and Cowan, 1977; Burwell and Amaral, 1998). Birds lack a corpus callosum, and in other avian circuits there is even less connection with the contralateral hemisphere than in mammals (Letzner et al, 2016; Wittek et al, 2021). This distinction is meaningful, likely accounting for some extreme lateralization of sensory and motor brain functions in birds (Graves and Goodale, 1977; Clayton, 1993; Vu et al, 1998; Long and Fee, 2008; Martinho et al, 2015; Martinho and Kacelnik, 2016).…”

Section: Resultsmentioning

confidence: 99%

Topography of inputs into the hippocampal formation of a food-caching bird

Applegate

Gutnichenko

Aronov

2023

Preprint

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The mammalian hippocampal formation (HF) is organized into domains associated with different functions. These differences are driven in part by the pattern of input along the hippocampal long axis, such as visual input to the septal hippocampus and amygdalar input to temporal hippocampus. HF is also organized along the transverse axis, with different patterns of neural activity in the hippocampus and the entorhinal cortex. In some birds, a similar organization has been observed along both of these axes. However, it is not known what role inputs play in this organization. We used retrograde tracing to map inputs into HF of a food-caching bird, the black-capped chickadee. We first compared two locations along the transverse axis: the hippocampus and the dorsolateral hippocampal area (DL), which is analogous to the entorhinal cortex. We found that pallial regions predominantly targeted DL, while some subcortical regions like the lateral hypothalamus (LHy) preferentially targeted the hippocampus. We then examined the hippocampal long axis and found that almost all inputs were topographic along this direction. For example, the anterior hippocampus was preferentially innervated by thalamic regions, while posterior hippocampus received more amygdalar input. Some of the topographies we found bear resemblance to those described in the mammalian brain, revealing a remarkable anatomical similarity of phylogenetically distant animals. More generally, our work establishes the pattern of inputs to HF in chickadees. Some of these patterns may be unique to chickadees, laying the groundwork for studying the anatomical basis of these birds' exceptional hippocampal memory.

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Section: Resultsmentioning

confidence: 99%

Topography of inputs into the hippocampal formation of a food-caching bird

Applegate

Gutnichenko

Aronov

2023

Preprint

View full text Add to dashboard Cite

show abstract

“…In the mammalian hippocampal circuit, the majority of input is from the ipsilateral hemisphere, though there are some contralateral projections (Burwell & Amaral, 1998; Goldowitz et al., 1975; Swanson & Cowan, 1977). Birds lack a corpus callosum, and in other avian circuits, there is even less connection with the contralateral hemisphere than in mammals (Letzner et al., 2016; Wittek et al., 2021). This distinction is meaningful, likely accounting for some extreme lateralization of sensory and motor brain functions in birds (Clayton, 1993; Graves & Goodale, 1977; Long & Fee, 2008; Martinho & Kacelnik, 2016; Martinho et al., 2015; Vu et al., 1998).…”

Section: Resultsmentioning

confidence: 99%

Topography of inputs into the hippocampal formation of a food‐caching bird

Applegate

Gutnichenko

Aronov

2023

J of Comparative Neurology

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The mammalian hippocampal formation (HF) is organized into domains associated with different functions. These differences are driven in part by the pattern of input along the hippocampal long axis, such as visual input to the septal hippocampus and amygdalar input to the temporal hippocampus. HF is also organized along the transverse axis, with different patterns of neural activity in the hippocampus and the entorhinal cortex. In some birds, a similar organization has been observed along both of these axes. However, it is not known what role inputs play in this organization. We used retrograde tracing to map inputs into HF of a food‐caching bird, the black‐capped chickadee. We first compared two locations along the transverse axis: the hippocampus and the dorsolateral hippocampal area (DL), which is analogous to the entorhinal cortex. We found that pallial regions predominantly targeted DL, while some subcortical regions like the lateral hypothalamus (LHy) preferentially targeted the hippocampus. We then examined the hippocampal long axis and found that almost all inputs were topographic along this direction. For example, the anterior hippocampus was preferentially innervated by thalamic regions, while the posterior hippocampus received more amygdalar input. Some of the topographies we found bear a resemblance to those described in the mammalian brain, revealing a remarkable anatomical similarity of phylogenetically distant animals. More generally, our work establishes the pattern of inputs to HF in chickadees. Some of these patterns may be unique to chickadees, laying the groundwork for studying the anatomical basis of these birds’ exceptional hippocampal memory.

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“…Interestingly, animal studies have contributed to the best understanding of CC function and in some instances, different species separated for millions of years demonstrated a curious decision-making process. Therefore, CC is a mammalian structure that increases as an evolutionary jump [ 32 ], and, therefore, birds have no CC and just a small anterior commissure, depicting simultaneous activity on both hemispheres during the decision-making process [ 33 ].…”

Section: Reviewmentioning

confidence: 99%

The Role of Neuroplasticity in Improving the Decision-Making Quality of Individuals With Agenesis of the Corpus Callosum: A Systematic Review

Furtado¹,

Bernardes²,

Nunes³

et al. 2022

Cureus

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Although individuals with agenesis of corpus callosum (ACC) possess intelligence coefficients within regular parameters, current studies have demonstrated decision-making compromise and potential negative social consequences. Furthermore, alternative pathways regarding brain connectivity in acallosal patients combined with cognitive therapy that would potentially mitigate such difficulties. Therefore, this study aimed to examine the current state of the art regarding brain foundations in the role of neuroplasticity by improving the decision-making quality in ACC. A systematic revision of literature was performed including studies conducted on non-syndromic ACC individuals and analyzing the impact of the potential role of neuroplasticity on the decision-making published to date. Studies with patients who underwent callosotomy were excluded. Experimental studies performed on animal models were included. During this period, 849 studies were identified; among them, 11 were eligible for qualitative analysis. Despite the paucity of evidence on this matter, patients with ACC present considerable decision-making difficulties mainly due to the functional connectivity impairment in the frontal lobes. Moreover, neuroplasticity was characterized by increased anterior commissure width as compared with controls. Notwithstanding, no studies were conducted on cognitive therapists managing this type of disease. Although the reorganization of inter-hemispheric bundles on anterior commissure has demonstrated the main natural neuroanatomic strategy in ACC, further evidence will be needed to clarify whether cognitive stimulus could improve the decision-making quality.

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Unihemispheric evidence accumulation in pigeons.

Cited by 5 publications

References 95 publications

Topography of inputs into the hippocampal formation of a food-caching bird

Topography of inputs into the hippocampal formation of a food-caching bird

Topography of inputs into the hippocampal formation of a food‐caching bird

The Role of Neuroplasticity in Improving the Decision-Making Quality of Individuals With Agenesis of the Corpus Callosum: A Systematic Review

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