Unilateral central retinal vein occlusion as a first manifestation of diabetes mellitus in a ten-year-old girl

Alduaij, Atheer Ali; Alhamad, Dhoha M; Schatz, Patrik

doi:10.1016/j.sjopt.2018.02.009

Cited by 3 publications

(1 citation statement)

References 13 publications

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“…Overall, reported risk factors include: APLA, [15][16][17][18][19] homocysteinemia, platelet over-responsiveness, 9,20 vasculitis, acute infections, inflammatory states, and optic pathway tumors. 3,11,[21][22][23][24][25][26][27] In some reports, more than one genetic abnormality was found in patients with RVO, suggesting synergistic interactions that may increase the risk. 28 As for SOVT cases, infectious etiologies.…”

Section: Discussionmentioning

confidence: 99%

Ocular venous occlusion in pediatrics: Should thrombophilia investigation and anticoagulant treatment be initiated?

Benish,

Shrot,

Barg

et al. 2023

Pediatric Blood & Cancer

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Retinal vein occlusion (RVO) and superior ophthalmic vein thrombosis (SOVT) are rare diseases in the pediatric population; however, the ophthalmic and neurologic morbidity are significant. As published data are scarce for these conditions, we present our experience with pediatric ocular venous thrombosis in four patients, and discuss recommended management for evaluation and treatment. We suggest performing thrombophilia workup for all pediatric patients with RVO or SOVT. In patients with thrombophilia risk factors or patients with additional thrombi, we highly recommend initiating anticoagulation therapy. There is a need for more research in order to determine the optimal management strategy.

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Section: Discussionmentioning

confidence: 99%

Ocular venous occlusion in pediatrics: Should thrombophilia investigation and anticoagulant treatment be initiated?

Benish,

Shrot,

Barg

et al. 2023

Pediatric Blood & Cancer

View full text Add to dashboard Cite

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Optic disk anatomical features of children with central retinal vein occlusion

Lei

Wan

Tehrani

et al. 2021

Journal of American Association for Pediatric Ophthalmology and

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Impact of high-risk optic disc on central retinal vein occlusion in patients with metabolic disorders

Si,

Lin,

Guo

et al. 2024

Front. Physiol.

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PurposeTo evaluate the impact of high-risk optic disc (HROD) on central retinal vein occlusion (CRVO) in patients with metabolic disorder(s).DesignRetrospective case-control study.MethodsA case-control study involving CRVO patients with metabolic disorder(s) was performed. PART I. All eligible patients with CRVO were included in CRVO group, and a similar number of patients with metabolic disorder(s) without CRVO were matched by sex, age and blood glucose level in the non-CRVO group. Various parameters were compared between groups. The impact of risk factors associated with CRVO was presented as odds ratios (ORs) and 95% confidence interval (95% CI). PART II. All eyes with CRVO that underwent intravitreal treatment (IVT) with a follow-up duration of ≥1 year were divided into non-HROD and HROD groups, and the differences between the two groups were compared.ResultsIn PART I, a total of 45 and 63 eyes were enrolled in the CRVO and non-CRVO groups, respectively, with a significant statistical difference in HROD (51.16% vs 26.98%, p = 0.010) between them. In further multivariate regression analysis, HROD was the independent risk factor for CRVO (OR = 5.036, 95% CI 1.847–13.729, p = 0.002). In PART II, demographic, follow-up information, treatment, and prognosis showed no significant statistical difference between the two groups (all p > 0.05).ConclusionHROD was likely to be an independent risk factor for CRVO occurrence in patients with metabolic disorder(s), but it did not affect the treatment and prognosis of CRVO eyes with HROD.

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Unilateral central retinal vein occlusion as a first manifestation of diabetes mellitus in a ten-year-old girl

Cited by 3 publications

References 13 publications

Ocular venous occlusion in pediatrics: Should thrombophilia investigation and anticoagulant treatment be initiated?

Ocular venous occlusion in pediatrics: Should thrombophilia investigation and anticoagulant treatment be initiated?

Optic disk anatomical features of children with central retinal vein occlusion

Impact of high-risk optic disc on central retinal vein occlusion in patients with metabolic disorders

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