Unilateral Gustatory Flushing: A Variant of Frey�s Syndrome?

Syndromes Affecting Ear Nose & Throat

“…The most widely accepted explanation for Frey's syndrome is the transection of postganglionic parasympathetic secretomotor fibres from the otic ganglion originally directed to the parotid gland, followed by aberrant re-innervation of the denervated facial cholinergic sweat glands and blood vessels. Mechanisms for flushing include misdirected regeneration or collateral sprouting of parasympathetic fibres into sympathetic pathways in the auriculotemporal and nearby nerves and/or release of bradykinin-producing enzymes by activated sweat glands resulting in vasodilatation [25]. Neurofibromatosis type II (NF2) is not a disorder of the inner ear may present with hearing loss (which can be of sudden onset), tinnitus and recurrent episodes of vertigo.…”