Unilateral Pigmented Paravenous Retinochoroidal Atrophy Associated With Presumed Ocular Tuberculosis

Abstract

This report describes a case of unilateral pigmented paravenous retinochoroidal atrophy (PPRCA) in a patient with low-grade unilateral intermediate uveitis. A 31-year-old woman, previously diagnosed with intermediate uveitis in the right eye (OD) presented to the clinic. Best-corrected visual acuity was 20/20 OD. Fundus examination, fluorescein angiography, autofluorescence, and optical coherence tomography OD were in keeping with a phenotypic diagnosis of PPRCA. Electrophysiology showed severe photoreceptor dysfunction of both the rod and the cone systems OD. Systemic workup revealed QuantiFERON-gold positive. This is the first report of unilateral PPRCA secondary to presumed ocular tuberculosis. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:345-349.].

Unilateral pigmented paravenous retinochoroidal atrophy with acute angle-closure glaucoma: a case report

“…It has been reported to be symmetrical in both eyes, non-progressive or slow progressive and prevalent in males [ 1 , 4 ]. PPRCA has been reported with cystoid macular oedema [ 5 ], intermediate uveitis [ 6 ], amblyopia [ 7 ] congenital glaucoma and strabismus [ 8 ] etc. There is no specific treatment for RPE or choriocapillaris atrophy.…”

“…Bozkurt et al described a patient of PPRCA and unilateral focal atrophic lesions in his mother and sister [ 16 ]. Guillermo et al described a case of unilateral PPRCA secondary to chronic inflammation with presumed tuberculous uveitis [ 6 ]. To the best of our knowledge, this is the first case of unilateral PPRCA with AACG which had no signs of existing or past inflammation.…”

Multimodal image characterization of paravenous atrophy

“…Differential diagnoses include chorioretinal degeneration and inflammatory diseases that cause chorioretinal atrophy, including RP (pericentral, sector and typical), helicoid peripapillary chorioretinal atrophy, serpiginous choroidopathy, angioid streaks, cone dystrophy or degeneration, Stickler syndrome, gyrate atrophy choroideremia, Wagner’s dominant vitreoretinal degeneration, sarcoidosis, syphilis, acute retinal necrosis, cytomegalovirus retinitis, tuberculous disseminated choroiditis, onchocerciasis, toxoplasmosis, frosted branch angiitis, and various disorders that are termed pseudoretinitis pigmentosa. We have to keep in mind that this entity could present as an isolated phenomena or be associated to other ocular disorder as Behcet’s disease (as we found in our case), tuberculosis or syphilis [ 12 ].…”

Idiopathic Retinal Vasculitis, Aneurysm and Neuroretinitis (IRVAN) and Pigmented Paravenous Chorioretinal Atrophy: Pathogenesis, Diagnosis, and Treatment

“…[39,42] Hastalık sıklıkla bilateral ve simetrik tutulum gösterir; ancak asimetrik ve tek taraflı olgular da literatürde bildirilmiştir. [43][44][45][46][47] Etyoloji bilinmemektedir. Sporadik ve kalıtsal olarak gelişebilmektedir.…”