Unilateral polymicrogyria: a common cause of hemiplegia of prenatal origin

Diffusion Tensor MR Imaging Tractography of the Pyramidal Tracts Correlates with Clinical Motor Function in Children with Congenital Hemiparesis

“…It is interesting to note that one third of our patients with moderate hemiparesis had unilateral polymicrogyria, which seems to be a common prenatal cause of congenital hemiparesis. 13 Despite the various causes of hemiparesis in our study (including some patients with no obvious cause for their hemiparesis), we were able to demonstrate a strong correlation of DTI metrics with the clinical severity of motor dysfunction. This is exciting because previous studies that correlate imaging findings with clinical hemiparesis are primarily limited to children with arterial infarcts as the cause of their hemiparesis, many of whom were diagnosed during the perinatal period.…”

Facial Hemangioma and Hemispheric Migration Disorder: Presentation of 5 Patients

“…Seizures associated with unilateral polymicrogyria in patients without facial hemangioma are controlled with antiepileptic medication in most patients. 16 The mechanism that causes polymicrogyria has not yet been fully clarified. Polymicrogyria was believed to be an arrest of neuroblast migration 17 but also a lesion acquired by an intrauterine vascular problem.…”

Three-Dimensional Reconstruction of Brain Surface Anatomy Based on Magnetic Resonance Imaging Diffusion-Weighted Imaging: A New Approach

“…Lee et al [6] introduced the use of 3D surface MR images for 24 cases of migrational defects, cortical dysplasia and prenatal asphyxia in which the precise configurations of cortical abnormalities, and their relation to the adjacent gyri and sulci were demonstrated. Pascual-Castroviejo et al [7] described a series of 13 patients who showed unilateral polymicrogyria. In this case, conventional MR studies performed in 4 cases failed to disclose polymicrogyria but revealed only an enlarged cortex that was diagnosed as cortical dysplasia.…”