Unilateral testicular vasculitis in polyarteritis nodosa mimicking a testicular torsion

Gervaise, A.; Junca-Laplace, Camille; Naulet, P.; Pernin, M.; Portron, Yann; Lapierre-Combes, M.

doi:10.1016/j.diii.2014.02.007

Cited by 4 publications

(3 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Many clinicians often neglect to consider testicular pain as a presenting symptom of vasculitis. To our best knowledge, our patient is the youngest of all the patients who had testicular pain as an initial manifestation of systemic PAN ( Table 1, [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18]). In addition to testicular pain, our patient displayed diffuse myalgias, unexplained weight loss meeting the diagnosing criteria for PAN [19].…”

Section: Discussionmentioning

confidence: 84%

Minocycline-Induced Polyarteritis Nodosa Presenting With Testicular Pain: A Case Report and Selected Review of the Literature

Findlay

Kwon

Sterling

et al. 2018

World J Nephrol Urol

View full text Add to dashboard Cite

Polyarteritis nodosa (PAN) is a systemic necrotizing vasculitis that affects small and medium-sized arteries, leading to aneurysm formation and ischemia in different organs of the body. Although not common, testicular manifestations have been documented. We discuss a case of 18-year-old male with minocycline-induced systemic PAN who presented with unilateral testicular pain. The definitive diagnosis was made after testicular biopsy demonstrating focally necrotizing vasculitis affecting small and medium vessels. Following the diagnosis he was discharged on prednisone, and was started on rituximab by his rheumatologist. He is clinically much improved during his surveillance follow-up visits with his rheumatologist and urologist. Minocycline-induced polyarteritis nodosa can present with constitutional symptoms and testicular pain among patients using the acne treatment. Prompt diagnosis is essential to ensure proper treatment and prevention of complications. Optimal management of these patients requires close collaboration amongst urologists and rheumatologists for accurate tissue diagnosis and close surveillance.

show abstract

Section: Discussionmentioning

confidence: 84%

Minocycline-Induced Polyarteritis Nodosa Presenting With Testicular Pain: A Case Report and Selected Review of the Literature

Findlay

Kwon

Sterling

et al. 2018

World J Nephrol Urol

View full text Add to dashboard Cite

show abstract

“…In these cases, radical orchidectomies were performed, and subsequent pathological examinations revealed the presence of histological features consistent with a diagnosis of PAN. Clinical symptoms of testicular involvement in PAN can also mimic a testicular torsion [18]. In isolated testicular vasculitis in PAN, orchiectomy is considered the main therapeutic approach, with a low risk of developing systemic PAN requiring pharmacotherapy after surgery [17].…”

Section: Polyarteritis Nodosa (Pan)mentioning

confidence: 99%

Urological Manifestations of the Systemic Vasculitides—A Scoping Review

Nowak

Krajewski

Krajewska

et al. 2021

Uro

View full text Add to dashboard Cite

Background: Vasculitides are specific inflammations of the blood vessel wall that can take place in any organ system of the human body. They may occur as a primary process (primary systemic vasculitides, PSV) or may be secondary to another underlying disease. In general, in association with the specific type of vasculitis, affected vessels vary in size, type, and location. In the following scoping review, we present clinical characteristics and manifestations of PSV with reference to the genitourinary system. Materials and methods: A non-systematic search of the relevant literature was conducted using three electronic databases (PubMed, Embase, and Web of Science) up to 29 October 2021. Results: Urogenital manifestations of PSV are infrequent, with the most commonly reported findings as prostatic or testicular involvements. However, almost all other organs of the genitourinary system can be affected. Conclusions: Because of the clinical heterogeneity and non-specific symptoms, the proper diagnosis of PSV is often delayed and constricted. Fast identification of urological manifestations of vasculitides is essential in implementing appropriate therapy and avoiding unnecessary, harmful, and invasive surgery.

show abstract

“…Many affected patients ended up with unilateral or bilateral orchiectomy because of misdiagnosis or testicular infarction caused by the late stage of disease. 7,8 Therefore, early identification and appropriate treatment are essential for patient care. Here, we report a case of ANCA-associated systemic vasculitis with testicular involvement as the first manifestation.…”

Section: Introductionmentioning

confidence: 99%

Testicular granulomatous vasculitis mimicking testicular torsion in an anti-neutrophil cytoplasmic antibody–associated vasculitis patient

Suo

Pérez

Finch

2019

SAGE Open Medical Case Reports

View full text Add to dashboard Cite

Testicular vasculitis is uncommon and can be easily misdiagnosed. Early identification and treatment are essential for patient care. A 63-year-old man, presenting with testicular pain and swelling, had been treated with antibiotics for weeks. A month later, he developed severe left testicular pain and systemic symptoms. Scrotal ultrasound was suggestive of testicular torsion due to no blood flow. Pathology of the orchiectomy specimen demonstrated testicular granulomatous vasculitis involving small- to medium-sized arteries. Additional work-up of blood tests contained positive antinuclear, anti-proteinase 3 and anti-myeloperoxidase antibodies. Erythrocyte sedimentation rate and C-reactive protein were also elevated. Diagnosis of anti-neutrophil cytoplasmic antibody–associated vasculitis was made and prednisone was started. During more than 1-year follow-up, the patient’s systemic symptoms were resolving gradually with no involvement of the other testis.

show abstract

Unilateral testicular vasculitis in polyarteritis nodosa mimicking a testicular torsion

Cited by 4 publications

References 5 publications

Minocycline-Induced Polyarteritis Nodosa Presenting With Testicular Pain: A Case Report and Selected Review of the Literature

Minocycline-Induced Polyarteritis Nodosa Presenting With Testicular Pain: A Case Report and Selected Review of the Literature

Urological Manifestations of the Systemic Vasculitides—A Scoping Review

Testicular granulomatous vasculitis mimicking testicular torsion in an anti-neutrophil cytoplasmic antibody–associated vasculitis patient

Contact Info

Product

Resources

About