Unilateral versus Bilateral Laparoscopic Ovarian Drilling in Clomiphene Citrate Resistant Polycystic Ovarian Syndrome in Minia Governate: Randomized Clinical Trial

Abstract

Background:The study explores unilateral versus bilateral laparoscopic ovarian drilling in patients with clomiphene citrate resistant polycystic ovarian syndrome in terms of improving the reproductive hormonal profiles, ovarian reserve and ovulation outcome in El-Minia Governate. Methods:The effectiveness of unilateral (N: 55 women) versus bilateral (N: 55 women) LOD were done in terms of improving infertility outcomes in clomiphene resistant PCOD patients. Results: There is no significant difference in both studied groups regarding serum FSH level before and six months after LOD in both groups (p > 0.05), however there is a significant difference in both studied groups regarding serum LH level before and six months after LOD (p < 0.001). However, no significant difference in serum LH levels either before or after LOD when compared both groups (p > 0.05). There is a significant difference in both studied groups regarding the serum AMH level before and six months after LOD in both groups (p < 0.001) , also there is a significant differences when compared the two groups after six months from LOD (p < 0.01).Conclusions: Unilateral laparoscopic ovarian drilling had similar efficacy as bilateral laparoscopic ovarian drilling in terms of restoration of normal menstrual cycles, ovulation and pregnancy rates with improving both ovarian reserve and AFC.