Unintentional Ingestion of Potassium Permanganate

Johnson, Thomas; Cassidy, David D.

doi:10.1097/01.pec.0000117926.65522.33

Cited by 22 publications

(27 citation statements)

References 11 publications

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“…Most of the corrosive substances ingested by the patients evaluated in our study contained sodium hydroxide, hydrochloric acid, sodium hypochlorite, or sulfuric acid. Patients who ingest potassium permanganate are rarely reported (11). In our series, 3 patients had ingested potassium permanganate.…”

Section: Discussionmentioning

confidence: 82%

Gastrointestinal system lesions in children due to the ingestion of alkali andacid corrosive substances

Demirören¹,

Kocamaz²,

Doğan³

2015

Turk J Med Sci

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The ingestion of corrosive substances among children mostly occurs accidentally. Most of these corrosive agents are household cleaners, and the esophagus is the most damaged site of the gastrointestinal system. Perforation and death are potential serious complications in the acute period, while stricture and cancer can occur over chronic periods of time. Endoscopic inspection in the early hours after ingestion is very important for the evaluation of the lesions to allow the planning of the appropriate treatment and follow-up care of these patients (1-3).In this study, we investigated children who were admitted to our clinic due to corrosive substance ingestion or suspected ingestion and who subsequently underwent an upper gastrointestinal endoscopy. The aim of this study was to examine esophageal and gastric lesions in children due to the ingestion of alkaline and acidic corrosive substances and to emphasize all relevant complications. Materials and methodsOne hundred and three children who were admitted to our pediatric gastroenterology unit during a 3-year period complaining of corrosive substance ingestion and who subsequently received upper gastrointestinal endoscopies were enrolled in this study. Clinical and endoscopic findings, treatment regimes, and long-term complications were retrospectively evaluated.The endoscopic procedure was first performed with a 5-mm diameter flexible endoscopy device (Olympus Evis Lucera CLV-260SL) 12-24 h after the ingestion of the corrosive substance in the patients admitted to our clinic. Before the procedure, 0.1-0.4 mg/kg intravenous midazolam was administered to sedate the patients.Background/aim: To examine esophageal and gastric lesions in children due to the ingestion of alkali and acid corrosive substances and to emphasize all related complications. Materials and methods:The reports of 103 children who ingested or were suspected to have ingested corrosive substances and who then underwent upper gastrointestinal endoscopic inspections were evaluated retrospectively.Results: Of the patients, the mean age was 41 ± 3.6 months, and 57.3% were male. Vomiting was the most common symptom (44.7%). Eighteen different commercial products were defined as corrosive substances: 59.2% of them were alkali, 39.8% were acids, and 1% had a neutral pH. These corrosive agents most frequently contained sodium hydroxide, followed by hydrochloric acid, sodium hypochlorite, and sulfuric acid. Endoscopic inspections were abnormal in 68% of the cases. Esophageal lesions were observed in 56.3% of the patients, while gastric lesions were observed in 35%. During the follow-up period, esophageal strictures developed in 4.9% of patients, while gastric outlet obstructions developed in 1%. Conclusion:Of the patients, the mean age was 41 ± 3.6 months, and 57.3% were male. Vomiting was the most common symptom (44.7%). Eighteen different commercial products were defined as corrosive substances: 59.2% of them were alkali, 39.8% were acids, and 1% had a neutral pH. These corrosive agents most frequently con...

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Section: Discussionmentioning

confidence: 82%

Gastrointestinal system lesions in children due to the ingestion of alkali andacid corrosive substances

Demirören¹,

Kocamaz²,

Doğan³

2015

Turk J Med Sci

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“…With the exception of NSAIDs, the number of case reports published describing chemical gastritis is significantly less than that for pill oesophagitis 16 17. Such injury may be asymptomatic; focal gastric injury is often observed at endoscopy in patients on NSAIDs or aspirin.…”

Section: Gastric Disordersmentioning

confidence: 99%

Drug-induced gastrointestinal disorders

Philpott

Nandurkar

Lubel

2013

Frontline Gastroenterol

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Drug-induced gastrointestinal disorders can mimic conditions, such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) and, hence, recognition can prevent unnecessary investigations and treatment. While the knowledge and awareness relating to the adverse gastrointestinal effects of some medications, such as non-steroidal anti-inflammatory drugs are well established, other commonly prescribed drugs, such as antipsychotics, antidepressants and metformin are less well understood and warrant further study. This review attempts to integrate recent information regarding adverse drug reactions and place this in a useful clinical context.

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“…10 Potassium permanganate is radiopaque and may be seen on radiographs of the chestandabdomen. 11 Laboratoryevaluation can include serum electrolytes, blood urea, nitrogen, creatinine, complete blood count, as well as liver or pancreatic function if indicated. With any signs of respiratory compromise, an arterial blood gas including a methemoglobin level may be warranted.…”

Section: Case Conclusion and Discussionmentioning

confidence: 99%