Unintentional Injuries among Psychiatric Outpatients with Major Depressive Disorder

Abstract

BackgroundNo study has investigated the percentages of and factors related to unintentional injuries among psychiatric outpatients with major depressive disorder (MDD). This study aimed to investigate these issues.MethodsOne-hundred and forty-one outpatients with MDD at baseline were enrolled from psychiatric outpatients by systematic sampling, and 119 subjects attended a one-year follow-up. Self-reported unintentional injuries in the past one year were recorded. Psychiatric disorders were diagnosed using the Structured Clinical Interview for DSM-IV-TR. The severity of depression was evaluated by the Hamilton Depression Rating Scale. Other data, including body weight and height, cigarette smoking, headaches, and medications, were collected. Generalized Estimating Equations were used to investigate independent factors related to unintentional injuries.ResultsAt baseline and follow-up, 40.4% and 27.7% of subjects had experienced at least one unintentional injury in the past one year, respectively. About half of subjects with unintentional injuries needed medical treatment for injuries and had functional impairment due to injuries. A greater severity of depression, cigarette smoking, a higher body mass index, and an older age were independent risk factors related to unintentional injuries.ConclusionUnintentional injuries that increased the medical burden and functional impairment were common among outpatients with MDD and should not be neglected. Treatment of depression, control of body weight, and quitting cigarettes might be helpful to prevent unintentional injuries.

Impact on mortality of being seropositive for hepatitis C virus antibodies among blood donors in Brazil: A twenty-year study

“…A recent meta-analysis has indicated that depression is the most prevalent HCV-associated extra-hepatic manifestation (24.5% in HCV-positive vs. 17.2% in HCV-negative individuals) [35]. Major depressive disorders have been associated with an increased risk of unintentional injuries and different types of trauma [18]. The increase in mortality associated with trauma in HCV-positive individuals observed in our study could be associated to a variable extent with a higher rate of risk behaviors among former illicit intravenous drug users and or people with psychiatric disorders.…”

“…During the study period (1994–2013) FPS screened all donors for HCV infection by enzyme-linked immunosorbent assay (ELISA) and RIBA HCV 3.0 strip immunoblot assay [18]. HCV-positive donors were defined as those who tested positive for EIA with RIBA HCV 3.0 or Western blot followed by a positive EIA [17, 19–21].…”

Survival analysis over a 20-year period of a Brazilian cohort of blood donors coinfected HIV-HCV

“…During the blood donation period (1994‒20132) FPS screened all donors for HCV infection by enzyme-linked immunosorbent assay (ELISA) and RIBA HCV 3.0 strip immunoblot assay. 14 HCV-positive donors were defined as those who tested positive for EIA with RIBA HCV 3.0 or Western blot followed by a positive EIA. 13 , 15 , 16 , 17 Nucleic Acid Amplification Tests (NAAT) for HCV diagnosis were not required in Brazil until November 2013.…”

Avaliação do risco e causas de óbito entre indivíduos diagnosticados com hepatite C através de exames de triagem para doação de sangue, no período de 1994 a 2016, em um hemocentro de São Paulo-SP

“…Além disso, uma redução significativa no uso de drogas injetáveis e no compartilhamento de agulhas foi observada 8,9,32 32 . Os transtornos depressivos maiores têm sido associados a um risco aumentado de lesões não intencionais e diferentes tipos de trauma 120…”