Unique Arterial Collaterals in the Presence of Renal and Aortic Occlusions

Salahudeen, A. K.; Pingle, A.; Barri, Z.

doi:10.1159/000185399

Nephron

1989

DOI: 10.1159/000185399

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Unique Arterial Collaterals in the Presence of Renal and Aortic Occlusions

A. K. Salahudeen¹,

A. Pingle²,

Z. Barri³

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Increased Oxygen Extraction as Adaptation to Acute Renal Ischemia

Ciocca¹,

Wilkerson²,

Conway³

et al. 1994

Journal of Investigative Surgery

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Acute renal ischemia is an infrequently encountered clinical entity with occasionally devastating consequences. The renal compensation to acute ischemia is unknown and is the purpose of this report. Eight pigs were anesthetized and ventilated. Left atrial, aortic, CVP, left renal venous, and ureteral catheters were inserted. Renal blood flow (RBF) reduction was accomplished by the graded constriction of the left renal artery using a balloon occluder. Renal oxygen extraction ratio (RER, %), renal oxygen delivery (RO2D, cc/min per 100 gm), renal oxygen consumption (RVO2, cc/min/100 gm), creatinine clearance (CrCl, ml/min), and renal lactate production (delta [L], mg/min per hgm) were measured at baseline and following sequential 90-minute intervals of moderate and then severe left renal flow reduction. Significant increases in renal oxygen extraction were observed when RBF was severely limited (.30 +/- .05 vs .64 +/- .06, p < .01). CrCl decreased precipitously (16.5 +/- 4.6 vs 0.2 +/- 0.07, p < .05). Lactate production by the ischemic organs correlated with blood flow reduction (r = .546, p = .0034). In severe ischemia, healthy kidneys increase oxygen extraction to preserve oxygen consumption.

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Increased Oxygen Extraction as Adaptation to Acute Renal Ischemia

Ciocca¹,

Wilkerson²,

Conway³

et al. 1994

Journal of Investigative Surgery

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Central hospital of Abu Dhabi: Forty years of service to the community (1968-2008)

Beshyah

2013

Ibnosina Journal of Medicine and Biomedical Sciences

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In 2008, the "Central Hospital" of Abu Dhabi closed, bringing to an end a long period of service to that community. The site was completely demolished, allowing room for further developments of Sheikh Khalifa Medical City. For 40 years, Abu Dhabi "Central Hospital" had been the main health center for the multi-ethnic community of Abu Dhabi. It was the seed for the local health care system, and its staff made significant health care and academic contributions, particularly in the field of nephrology, infectious disease, and emergency medicine. Its academic contributions were remarkable, relative to its modest facilities. This history note aims to commemorate the life and contributions of this small, yet pioneering, institution to the health services, medical education, and research in the capital of this new nation. It gives an opportunity to pay tribute to all those who served in it at any stage of their career.

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Unique Arterial Collaterals in the Presence of Renal and Aortic Occlusions

Cited by 2 publications

References 0 publications

Increased Oxygen Extraction as Adaptation to Acute Renal Ischemia

Increased Oxygen Extraction as Adaptation to Acute Renal Ischemia

Central hospital of Abu Dhabi: Forty years of service to the community (1968-2008)

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