Unique endoscopy findings in collagenous colitis

Couto, Gilberto; Bispo, Miguel; Barreiro, Pedro; Monteiro, Lucília; Matos, Leopoldo

doi:10.1016/j.gie.2008.06.010

Cited by 14 publications

(9 citation statements)

References 14 publications

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“…As we emphasize in our case report, 5 we do agree with the proposed mechanism of colonic mucosal tearing of Dr Koulaouzidis, in line with the hypothesis of Cruz-Correa et al 6 …”

Section: Responsesupporting

confidence: 93%

Response

Couto

Bispo

Barreiro

et al. 2010

Gastrointestinal Endoscopy

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“…As we emphasize in our case report, 5 we do agree with the proposed mechanism of colonic mucosal tearing of Dr Koulaouzidis, in line with the hypothesis of Cruz-Correa et al 6 …”

Section: Responsesupporting

confidence: 93%

Response

Couto

Bispo

Barreiro

et al. 2010

Gastrointestinal Endoscopy

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“…The diagnosis of microscopic colitis is obtained both by history, including medication use and endoscopy with histology. Endoscopic evaluation of the colon is almost always normal, but can occasionally show erythema and oedema and rarely proximal mucosal tears 86–89 . Colonic ulcer has been reported, possibly related to use of non‐steroidal anti‐inflammatory drugs 87 …”

Section: Diagnosismentioning

confidence: 99%

Review article: microscopic colitis - lymphocytic, collagenous and ‘mast cell’ colitis

Yen¹,

Pardi²

2011

Alimentary Pharmacology &Amp; Therapeutics

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Aliment Pharmacol Ther 2011; 34: 21–32 Summary Background Microscopic colitis is a relatively common cause of chronic diarrhoea in predominantly older adults, traditionally termed lymphocytic colitis and collagenous colitis. Increased mast cells found in the colonic biopsies of some patients with chronic diarrhoea may represent a distinct type of microscopic colitis. Aim To provide an updated review of the epidemiology, diagnosis and treatment of microscopic colitis, and to discuss the role of mast cells in the gastrointestinal tract and their potential role in cases of functional diarrhoea. Method A MEDLINE literature search was performed to identify pertinent articles. Relevant clinical abstracts were also reviewed. Results Incidence rates of microscopic colitis (lymphocytic and collagenous colitis) have increased over time, to levels comparable with other forms of inflammatory bowel disease. The possibility of drug‐induced microscopic colitis and concomitant coeliac sprue are important considerations when evaluating these patients. There are few controlled treatment trials in microscopic colitis, with much of the data on treatment coming from retrospective studies. Mast cells have been implicated in functional bowel disorders, with increased mast cells possibly contributing to cases of otherwise unexplained chronic diarrhoea, although this concept requires further investigation. Conclusions In patients with microscopic colitis, a systematic approach to therapy often leads to satisfactory control of symptoms. The role of mast cells in chronic diarrhoea represents an evolving field, with the potential to offer alternative treatment pathways in patients with otherwise unexplained functional diarrhoea.

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“…Particularly, there have been a few case reports of patients taking lansoprazole who had macroscopic features of superficial lacerations and linear mucosal tears on colonoscopy, but then diagnosed with collagenous colitis after biopsies [5,6]. It is imperative that patients found to have MC in the setting of macroscopic features on colonoscopy still be thoroughly worked up for other etiologies including medications, celiac disease, IBD, and autoimmune disorders.…”

Section: Discussionmentioning

confidence: 99%