Unique side-chain conformation encoding for chirality and azimuthal orientation in the molecular packing of skin collagen

Katz, Elton P.; David, Carl W

doi:10.1016/0022-2836(92)90878-n

Cited by 34 publications

(27 citation statements)

References 20 publications

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“…Several recent studies addressing molecular packing of collagen are pertinent to this question. Katz and David [19] conducted a detailed analysis of molecular packing in type I collagen from skin, in which they identified specific regions encoding for chirality and orientation, both of which have been reported to affect second harmonic intensity. Specifically, they identified a sequence of three amino acids that, when present in all three chains, leads to a conformational change that increases molecular helicity.…”

Section: Discussionmentioning

confidence: 99%

Collagen structure and nonlinear susceptibility: Effects of heat, glycation, and enzymatic cleavage on second harmonic signal intensity

et al. 2000

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Section: Discussionmentioning

confidence: 99%

Collagen structure and nonlinear susceptibility: Effects of heat, glycation, and enzymatic cleavage on second harmonic signal intensity

et al. 2000

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“…29 This nonequivalent environment of the same residue in the three chains may have implications for the association of collagen molecules into larger aggregates in their functional state or the specific binding sites of collagens. A possible consequence of this inequivalence might be a nonsymmetric character of the collagen triple helix, 38 which could give rise to non symmetric supermolecular aggregates.…”

Section: Figurementioning

confidence: 99%

Conformational analysis and stability of collagen peptides by CD and by1H- and13C-NMR spectroscopies

Consonni¹,

Zetta²,

Longhi

et al. 2000

Biopolymers

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“…Moreover, the dipoles of water molecules contribute to the polar nature of collagen [23], as they exist in a hydrated state during the process of wet bonding. Molecular modeling of collagen with adjacent charged residues predicted that side-chains participate in the formation of intra-chain and inter-helix ion pairs [24,25]. Moreover, proteoglycans associated with dentin collagen fibrils are characterized by lateral glycosaminoglycans chains with negatively charged residues that are responsible for the high water binding and tissue swelling behavior of this collagen-proteoglycan complex [26,27].…”

Section: Fig 2 -Fe-sem Micrographs Of Bonded Interfaces In Single Bomentioning

confidence: 99%

Electric device improves bonds of simplified etch-and-rinse adhesives

et al. 2007

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d e n t a l m a t e r i a l s 2 3 ( 2 0 0 7 ) 513-518 a v a i l a b l e a t w w w . s c i e n c e d i r e c t . c o m j o u r n a l h o m e p a g e : w w w . i n t l . e l s e v i e r h e a l t h . c o m / j o u r n a l s / d e m a Objectives. This study investigated the effects of an electric field produced by a new device for the application of etch-and-rinse adhesives on demineralized dentin surfaces. Electric device improves bonds of simplified etch-and-rinse adhesives Methods. Three simplified etch-and-rinse adhesives (Single Bond, Prime&Bond NT and One-Step) were applied with the electric device and compared with controls prepared with disposable sponges. Specimens were processed for microtensile bond strength test and nanoleakage investigation using high resolution SEM.Results. Microtensile testing revealed higher bond strengths (p < 0.05) for all adhesives tested when electricity was used. Adhesive interfaces prepared with electric impulses exhibited very homogenous hybrid layers with minimal nanoleakage compared with the controls.Significance. The use of electricity produced by a new electronic device during the application of dentin adhesives may increase adhesive adaptation to the dentin substrate and improve dentin hybridization due to the substrate modifications induced by an electric field on the demineralized dentin organic matrix. IntroductionDespite the recent developments in adhesive dentistry to reduce the number of working steps and to simplify the clinical procedure, the new simplified adhesives do not produce better results in in vitro tests [1] or improve clinical efficacy [2]. Ironically, the most user-friendly simplified adhesives, the socalled self-etching one-step adhesives, exhibited the lowest bond strengths and the least predictable clinical performances over time when compared with the multi-step etch-and-rinse and self-etch systems [2,3]. Previous reports have shown that one of the major disadvantages of the etch-and-rinse systems is incomplete infiltra- * Corresponding author at: UCO of Dental Sciences, University of Trieste, Via Stuparich, 1, I-34129 Trieste, Italy. Tel.: +39 040 3992192; fax: +39 040 912579.E-mail address: lbreschi@units.it (L. Breschi).tion of the exposed dentin matrix due to the collapse of the collagen fibrils after removal of the mineral phase [4][5][6]. A layer of disrupted collagen fibrils may interfere with adhesive penetration and the formation of the hybrid layer. Incompletely infiltrated voids within these hybrid layers may be revealed with a tracer such as silver nitrate using transmission (TEM) or scanning electron microscopy (SEM). Tracer infiltration in the absence of a physical interfacial gap has been referred to as nanoleakage [4], which may occur in interfaces bonded with either etch-and-rinse or self-etch adhesives. Field emission-SEM (FE-SEM) and TEM studies showed that entrapment of water within adhesive interfaces may create additional voids or tracks that could be revealed by these tracers [7][8][9].

show abstract

Unique side-chain conformation encoding for chirality and azimuthal orientation in the molecular packing of skin collagen

Cited by 34 publications

References 20 publications

Collagen structure and nonlinear susceptibility: Effects of heat, glycation, and enzymatic cleavage on second harmonic signal intensity

Collagen structure and nonlinear susceptibility: Effects of heat, glycation, and enzymatic cleavage on second harmonic signal intensity

Conformational analysis and stability of collagen peptides by CD and by1H- and13C-NMR spectroscopies

Electric device improves bonds of simplified etch-and-rinse adhesives

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