We prove that simple, separable, monotracial UHF L p -operator algebras are not classifiable up to (complete) isomorphism using countable structures, such as K-theoretic data, as invariants. The same assertion holds even if one only considers UHF L p -operator algebras of tensor product type obtained from a diagonal system of similarities. For p = 2, it follows that separable nonselfadjoint UHF operator algebras are not classifiable by countable structures up to (complete) isomorphism. Our results, which answer a question of N. Christopher Phillips, rely on Borel complexity theory, and particularly Hjorth's theory of turbulence.2000 Mathematics Subject Classification. Primary 47L10, 03E15; Secondary 47L30.