SummaryAutonomy is becoming a prime requirement for satellite mission control operations. Data‐driven methods like Machine Learning models are playing a key role in bringing in autonomy. Health keeping data from satellite telemetry is a key ingredient in these data‐driven methods. In real‐world satellite operations, the health‐keeping telemetry data gradually drifts due to adverse space weather effects and wear and tear of electronic and mechanical components. The key question that arises is how to detect and quantify the data drift which is generally a gradual phenomenon. This paper discusses a novel statistical method for detecting data drift occurring in satellite telemetry. For the purpose of experimental work in this paper, an actual telemetry data set of the BUS CURRENT sensor which is part of the Electrical Power System of a Low Earth Orbit Satellite was considered. Data drift detection test was carried out using this sensor data using the developed novel statistical method and with Kolmogorov Smirnov test which is a probabilistic method. Both results are analysed and compared. Thereafter novel statical method was used to check its efficacy using a synthetic data set with induced drift.