2024
DOI: 10.1016/j.bios.2023.115929
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Universal smartphone-assisted label-free CRISPR/Cas12a-DNAzyme chemiluminescence biosensing platform for on-site detection of nucleic acid and non-nucleic acid targets

Hui Chen,
Ying Feng,
Feng Liu
et al.
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Cited by 17 publications
(3 citation statements)
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“…Yanxia Li et al developed a highly sensitive chemiluminescence metallo immunoassay for H1N1 inuenza virus detection, with Other detection methods CRISPR-Cas technology is widely used in elds such as gene editing, and recently researchers have also applied it to the eld of virus detection. 161,162 The detection method based on CRISPR-Cas technology has the advantages of high sensitivity, speci-city, and rapidity, which is one of the hotspots for future development. 163,164 Using the targeting of the CRISPR-Cas system, clusters of regularly spaced short palindromic repeats are combined with amplied target DNA, and combined with uorescence labelling and other detection methods, inuenza A virus RNA can be rapidly and accurately detected.…”
Section: Chemiluminescence (Cl)-based Detection Assaysmentioning
confidence: 99%
“…Yanxia Li et al developed a highly sensitive chemiluminescence metallo immunoassay for H1N1 inuenza virus detection, with Other detection methods CRISPR-Cas technology is widely used in elds such as gene editing, and recently researchers have also applied it to the eld of virus detection. 161,162 The detection method based on CRISPR-Cas technology has the advantages of high sensitivity, speci-city, and rapidity, which is one of the hotspots for future development. 163,164 Using the targeting of the CRISPR-Cas system, clusters of regularly spaced short palindromic repeats are combined with amplied target DNA, and combined with uorescence labelling and other detection methods, inuenza A virus RNA can be rapidly and accurately detected.…”
Section: Chemiluminescence (Cl)-based Detection Assaysmentioning
confidence: 99%
“…7–9 The latest research in this field predominantly revolves around enhancing optical and biochemical sensors, refining motion detectors, and improving environmental sensors. 10–12…”
Section: Introductionmentioning
confidence: 99%
“…CL assays are particularly suited for the development of miniaturized and portable analytical devices, as the instrumentation required for the readout of the CL signal is very simple, mainly requiring a photon detection device and a dark chamber to avoid interference from ambient light. Indeed, light imaging systems based on a charge-coupled device (CCD) camera [44][45][46] or even a smartphone's complementary metal-oxide semiconductor (CMOS) sensor [47][48][49][50][51] were employed and integrated into a compact and portable device for photon detection [39].…”
Section: Introductionmentioning
confidence: 99%