Universal <sup>99m</sup>Tc Generator for Human Use

Milenković, S.; Vučina, J. L.; Jaćimović, Lj.; Karanfilov, E. S.; Memedović, T.

doi:10.1080/10256018308544845

Cited by 7 publications

(1 citation statement)

References 2 publications

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“…The generators are calibrated up to six days in advance so that they can be transported to the users distant from the production cite. The activities are 3.7, 7.4, 11.1 and 18.5 GBq at the time of calibration [4].…”

Section: Molybdenum-99/technetium-99m Generatorsmentioning

confidence: 99%

Radionuclidic generators for the production of technetium-99m and rhenium-188

Vučina

Lukic

2002

Facta Univ Phys Chem Technol

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The paper deals with production and application of open radioactive sources in modern diagnostic and therapeutic nuclear medicine. In principle, besides adequate physical, chemical and biological properties a reliable route for the routine production of both radionuclide and radiopharmaceutical should be on disposal. The favorite route are radionuclidic generators as they enable simple production of shorter-lived radionuclides at relatively low costs. The main radionuclide in diagnosis is technetium-99m. Its advantages are favorable nuclear properties, availability of large activities of high quality 99mTc at reasonable prices by using (n,f)99Mo/99mTc generators and versatile chemistry. It is used in the investigation of practically all organs and tissues in the human body. Among the betaemitters the radionuclides of rhenium have been recently proposed as suitable candidates for therapeutic applications. The most important is 188Re which is obtained from 188W/188Re generator. Some of the important radiopharmaceuticals labeled with rhenium radionuclides used for certain specific indications are also shown. The activities performed in the Laboratory for Radioisotopes (Vinča Institute of Nuclear Sciences) are also enclosed

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Section: Molybdenum-99/technetium-99m Generatorsmentioning

confidence: 99%

Radionuclidic generators for the production of technetium-99m and rhenium-188

Vučina

Lukic

2002

Facta Univ Phys Chem Technol

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Separation of99Mo from132Te using thiourea as complexing agent. Application to the separation of99Mo from fission products

Mestnik

Silva

1993

Journal of Radioanalytical and Nuclear Chemistry, Articles

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Radiopharmaceutical complexes of technetium and tin: Physicochemical and biochemical research

Vanlić-Razumenić

1999

J Radioanal Nucl Chem

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The list of the developed 99mTc-kits in our research center is given, while the whole research work as a basis of 99mTc scanning agents production is described. Research involved physico-chemical studies of both types of complexes: tin and technetium-99 complexes as model compounds for 99mTc-radiopharmaceuticals, as well as biochemical studies including interaction with blood proteins, as well as subcellular localization of certain 99mTc ' 99Tc-complexes.

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Universal ^99mTc Generator for Human Use

Cited by 7 publications

References 2 publications

Radionuclidic generators for the production of technetium-99m and rhenium-188

Radionuclidic generators for the production of technetium-99m and rhenium-188

Separation of99Mo from132Te using thiourea as complexing agent. Application to the separation of99Mo from fission products

Radiopharmaceutical complexes of technetium and tin: Physicochemical and biochemical research

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Universal 99mTc Generator for Human Use

Cited by 7 publications

References 2 publications

Radionuclidic generators for the production of technetium-99m and rhenium-188

Radionuclidic generators for the production of technetium-99m and rhenium-188

Separation of99Mo from132Te using thiourea as complexing agent. Application to the separation of99Mo from fission products

Radiopharmaceutical complexes of technetium and tin: Physicochemical and biochemical research

Contact Info

Product

Resources

About

Universal ^99mTc Generator for Human Use