“…Of these, the 1376 mutation is the most common allele, accounting for nearly 55% of deficiency cases in the Chinese population of Taiwan [2,3,6]. In contrast, the 493 and 592 mutations are two major mutant alleles for the Saisiat and the Ami, respectively [4], In this communication, we report a novel G6PD mutation (517 T->C; 173 Phe->Leu) found in a Chinese infant with neonatal jaun- with modification [17], Briefly, the whole-blood sam ple or pre-extractcd patient's DNA was subjected to PCR amplification using G6PD-specific primer sets that covered the entire coding region of the G6PD gene [15,17], The PCR amplification procedure was per formed as previously described [ 15 . 17], The amplified PCR-SSCP products were analysed in a mini-gel sys tem and by ethidium bromide staining.…”