The family of elliptical gears with closed pitch curves includes elliptical gears and deformed elliptical gears. Elliptical gears are not only the most widely used non-circular gears but also the research hotspot in the field of non-uniform transmission. However, adjusting the shape of its pitch curve is difficult, which seriously restricts its popularization. This article proposes a piecewise deformed elliptical gear with a closed pitch curve, which realizes the unity of all kinds of elliptical gears in the mathematical model, makes the shape of the pitch curve and gear ratio easier to adjust, and expands the connotation and application scope of the family of elliptical gears. Moreover, the design approach of transmission with piecewise deformed elliptical gear was studied, and the inspection method of transmission performance was provided. The internal relationship between piecewise deformed elliptical gears and the family of elliptical gears was then analyzed. Finally, the method of computer-aided design (CAD) system developed was also provided. Additionally, a case was provided to verify the above theories. The designed conjugate pair can realize a correct meshing and adjust the gear ratio more flexibly, laying a theoretical foundation to expand the application field of non-uniform transmission.