2023
DOI: 10.21203/rs.3.rs-3055146/v1
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Unlocking the Potential of Micromonospora sp.: Metabolomics and Molecular Modeling to Combat Antibiotic Resistance in Enteric Pathogens via ATP Synthase Inhibitors

Sahar A. El-Shatoury,
Hanan K. Megawer,
Mohamed S. Nafie
et al.

Abstract: Background The misuse of antibiotics in the last decade led to the quick emergence of antibiotic resistance among pathogenic microorganisms. It has become a serious health problem that motivates researchers to explore new antimicrobial compounds. Micromonospora is one of the most important producers of commercially successful secondary bioactive metabolites, especially antibiotics such as aminoglycosides, enediynes, and oligosaccharides. This study highlights the potential of Micromonospora spp. as a source o… Show more

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