2024
DOI: 10.1071/ch24075
|View full text |Cite
|
Sign up to set email alerts
|

Unlocking therapeutic potential: the role of adamantane in drug discovery

Chianna Dane,
Grace A. Cumbers,
Beau Allen
et al.

Abstract: The unique structural and physicochemical properties of adamantane and its derivatives have attracted considerable attention in the field of medicinal chemistry. Substituting phenyl rings for adamantane or its derivatives has provided a promising strategy to introduce lipophilicity and escape the ‘flat land’ of modern drug discovery. Additionally, the unique three-dimensional structure of adamantane facilitates the precise positioning of substituents allowing for a more effective exploration of drug targets. E… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Year Published

2024
2024
2024
2024

Publication Types

Select...
2

Relationship

0
2

Authors

Journals

citations
Cited by 2 publications
references
References 58 publications
0
0
0
Order By: Relevance