Unlocking vendor-specific tags: Three-dimensional printing of echocardiographic data sets

Hosny, Ahmed; Shen, Tao; Kuo, Alexander S.; Long, David P.; Andrawes, Michael N.; Dilley, Joshua D.

doi:10.1016/j.jtcvs.2017.08.064

Cited by 8 publications

(8 citation statements)

References 3 publications

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“…Therefore, the next iteration of the algorithm is to adapt the same approach, serially dilating a binary image, to a 3-dimensional object, where automatically defining a centerline is currently beyond the capabilities of current imaging programs. Such an algorithm would have wide applications both clinically and experimentally in the cardiac field alone, including 3D cardiac echocardiograms 22 23 , 3D electron microscopy 24 25 26 , and 3D magnetic resonance imaging 27 28 29 .…”

Section: Discussionmentioning

confidence: 99%

Quantifying Intermembrane Distances with Serial Image Dilations

Raisch

Khan

Poelzing

2018

JoVE

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A recently-described extracellular nanodomain, termed the perinexus, has been implicated in ephaptic coupling, which is an alternative mechanism for electrical conduction between cardiomyocytes. The current method for quantifying this space by manual segmentation is slow and has low spatial resolution.We developed an algorithm that uses serial image dilations of a binary outline to count the number of pixels between two opposing 2 dimensional edges.This algorithm requires fewer man hours and has a higher spatial resolution than the manual method while preserving the reproducibility of the manual process.In fact, experienced and novice investigators were able to recapitulate the results of a previous study with this new algorithm.The algorithm is limited by the human input needed to manually outline the perinexus and computational power mainly encumbered by a pre-existing pathfinding algorithm.However, the algorithm's high-throughput capabilities, high spatial resolution and reproducibility make it a versatile and robust measurement tool for use across a variety of applications requiring the measurement of the distance between any 2-dimensional (2D) edges.

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Section: Discussionmentioning

confidence: 99%

Quantifying Intermembrane Distances with Serial Image Dilations

Raisch

Khan

Poelzing

2018

JoVE

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“…org) 16 . The medical images information was provided in the nearly raw raster data (NRRD) format which is a file format designed to support scientific visualization and to process images involving N-dimensional raster data 17 .…”

Section: Geometry Model Of the Studymentioning

confidence: 99%

Comportamiento biomecánico de tejido óseo en fijaciones de columna

Alpizar-Aguirre¹,

González-Carbonell²,

Ortiz-Prado³

et al. 2020

CIRU

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Background:The mechanical fixation of the spine in patients with osteoporotic vertebral degeneration is a challenge for surgeons, the vertebrae selected to insert the screws may fail, endangering health and even patient's life. Objective: The objective of the study was to study the effect of the variation of the bone density in the bone-screw interface from a three-dimensional model of the lumbar section. Materials and methods: The finite element method was used to model the behavior of the lumbar vertebral section when applying compression loads. Results: The stresses between 2 and 3 MPa were located on the contact surface with the screw, both in the vertebral body and in the apophysis, being slightly higher in the vertebral body. Conclusions: Regardless of bone density, the contact zones between the screws are susceptible to bone tissue failure. The posterior half of the vertebral body was the most sensitive to high values of stress, while in the areas furthest from the axis of the screw stress tended to their minimum.

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“…In the biomedical engineering field, additive manufacturing technology can be used for various applications, such as tissue and organ fabrication [3], implant and prostheses production [4], drug delivery [5], and production of anatomical structures [6]. In the clinical research area, especially, 3Dprinted anatomical models with realistic anatomical organ shaped structures have been used as experimental models for presurgical planning through rehearsing and preparing complex surgical procedures [7][8][9] to reduce the risk and time on the operating table, as well as education and training [10]. Besides, anatomical 3D printing can demonstrate the performance of the newly developed biomedical products [11].…”

Section: Introductionmentioning

confidence: 99%

Manufacturing and Characterization of Hybrid Bulk Voxelated Biomaterials Printed by Digital Anatomy 3D Printing

et al. 2020

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The advent of 3D digital printers has led to the evolution of realistic anatomical organ shaped structures that are being currently used as experimental models for rehearsing and preparing complex surgical procedures by clinicians. However, the actual material properties are still far from being ideal, which necessitates the need to develop new materials and processing techniques for the next generation of 3D printers optimized for clinical applications. Recently, the voxelated soft matter technique has been introduced to provide a much broader range of materials and a profile much more like the actual organ that can be designed and fabricated voxel by voxel with high precision. For the practical applications of 3D voxelated materials, it is crucial to develop the novel high precision material manufacturing and characterization technique to control the mechanical properties that can be difficult using the conventional methods due to the complexity and the size of the combination of materials. Here we propose the non-destructive ultrasound effective density and bulk modulus imaging to evaluate 3D voxelated materials printed by J750 Digital Anatomy 3D Printer of Stratasys. Our method provides the design map of voxelated materials and substantially broadens the applications of 3D digital printing in the clinical research area.

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Unlocking vendor-specific tags: Three-dimensional printing of echocardiographic data sets

Abstract: Three-dimensional rendering of a normal aortic valve in midsystole. Central MessageThis study aims to unlock vendor-specific tags and establish an open-source workflow for generating 3-dimensional anatomic models of cardiac structures from routine echocardiographic data sets.

Cited by 8 publications

References 3 publications

Quantifying Intermembrane Distances with Serial Image Dilations

Quantifying Intermembrane Distances with Serial Image Dilations

Comportamiento biomecánico de tejido óseo en fijaciones de columna

Manufacturing and Characterization of Hybrid Bulk Voxelated Biomaterials Printed by Digital Anatomy 3D Printing

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