Unmasking Brugada-Type Electrocardiogram on Deep Inspiration

Beat-to-Beat Variability in Preload Unmasks Latent Risk of Torsade de Pointes in Anesthetized Chronic Atrioventricular Block Dogs

“…38 Our data confirm the usefulness of STVMAPD for arrhythmic risk prediction, but with the important finding that a controlled challenge is required. This opens perspective to apply changes in preload to increase the predictive value of STV of repolarization for arrhythmias.…”

Risk Stratification in Patients With Brugada Syndrome Without Previous Cardiac Arrest

“…Interestingly, ECG recording on deep inspiration has been reported to be useful to identify Brugada ECG. 20 Accordingly, repeated recordings of 12-lead ECG should be performed to increase the detection of Sp1.…”

A case of Brugada pattern “bigeminy”

“…We might hypothesize that a marked dominance of Ito or an inhibition of ICa, INa occurred in a 1:1 fashion resulting in a “bigeminy‐like” Brugada type 1 pattern. A previous study showed that the deep inspiration was able to unmask a Brugada pattern 4 . During deep inspiration indeed the heart is pulled downward as the diaphragm falls following lung expansion, leading the right precordial leads at conventional lead positions (V 1 –V 3 ) to be closer to the right ventricular outflow tract.…”