Unmasking Influenza Virus Infection
in Patients Attended to in the Emergency
Department

Monmany, J.; Rabella, N; Margall, N; Domingo, Peré; Gich, Ignasi; Vázquez, Guillermo

doi:10.1007/s15010-004-3088-y

Cited by 39 publications

(42 citation statements)

References 33 publications

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“…In contrast to other studies, 8,16,18,23 this study found no effect of age on presentation. Cough alone had the highest sensitivity (91%), while fever had a sensitivity of 50%.…”

Section: Discussioncontrasting

confidence: 99%

See 1 more Smart Citation

Case-Control Study of Clinical Features of Influenza in Hospitalized Patients

Babcock

Merz

Dubberke

et al. 2008

Infect. Control Hosp. Epidemiol.

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“…In contrast to other studies, 8,16,18,23 this study found no effect of age on presentation. Cough alone had the highest sensitivity (91%), while fever had a sensitivity of 50%.…”

Section: Discussioncontrasting

confidence: 99%

“…1 The clinical characteristics of influenza infection have been well described for outpatients, 2-7 emergency department patients, 8,9 and nursing home residents. 10 Several different case definitions have been proposed for influenza in those populations.…”

Section: Case-control Study Of Clinical Features Of Influenza In Hospmentioning

confidence: 99%

Case-Control Study of Clinical Features of Influenza in Hospitalized Patients

Babcock

Merz

Dubberke

et al. 2008

Infect. Control Hosp. Epidemiol.

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“…Many studies have described the clinical presentation of influenza in outpatient settings, 2-7 emergency departments, 8,9 and long-term care facilities. 6 Several meta-analyses have also addressed the clinical features of influenza in outpatients.…”

Section: Discussionmentioning

confidence: 99%

“…The difficulties of identifying influenza virus infection on the basis of clinical characteristics have been well described for outpatients, [2][3][4][5][6][7] patients in the emergency department, 8,9 and residents of nursing homes. 10 There are fewer recent data regarding the clinical presentation of hospitalized patients with influenza.…”

Section: Infect Control Hosp Epidemiolmentioning

confidence: 99%

Is Influenza an Influenza-Like Illness? Clinical Presentation of Influenza in Hospitalized Patients

Babcock

Merz

Fraser

2006

Infect. Control Hosp. Epidemiol.

114

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“…The difficulties in identifying influenza virus infection on the basis of clinical characteristics have been well documented [5][6][7][8][9]. Several studies have shown that a high fever and cough represent best predictors for influenza infection in adults while influenza virus circulates in any given community [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Differences in clinical predictors of influenza in adults and children with influenza-like illness

Sočan¹,

Prosenc²,

Nagode

2010

Open Medicine

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AbstractInfluenza contributes significantly to morbidity and mortality in the winter season. The aim of the study was to identify clinical signs and symptoms most predictive of influenza infection in children and adults with influenza-like illness. A prospective systematic sampling analysis of clinical data collected through sentinel surveillance system for influenza in 32 primary care centers and one tertiary care hospital in Slovenia during two consecutive influenza seasons (2004/2005 and 2005/2006) was carried out. Children and adults who had influenza-like illness, defined as febrille illness with sudden onset, prostration and weakness, muscle and joint pain and at least (cough, sore throat, coryza) were included and tested for influenza A and B virus, adenovirus, respiratory syncytial virus and enterovirus by RT-PCR. Clinical data were evaluated in statistical models to identify the best predictors for the confirmation of influenza for children (under age of 15) and adults. Of 1,286 patients with influenza-like symptoms in both seasons 211 were confirmed to have influenza A or B alone and compared to 780 influenza-negative patients. A fever over 38°C, chills, headache, malaise and sore eyes revealed a significant association with positive RT-PCR test for influenza virus in children. In adults, only three symptoms were significantly related to PCR-confirmed influenza infection: fever, cough and abnormal breath sounds. The stepwise logistic regression analysis showed that four symptoms predicted influenza in children: fever (38°C or more) (p=0.010), headache (p=0.030), cough (p=0.044) and absence of abnormal breathing sounds (p=0.015) with sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 5.1%, 98.1%, 57.1% and 80.1%, respectively. For adults, the strongest impact on influenza positivity was found for fever (p=0.008) and cough (p=0.085). The model for adults had less favorable characteristics, with sensitivity, specificity, PPV and NPV of 0%, 100%, 0% and 76.4%, respectively. Differences in clinical predictors of influenza in children compared to adults were found. The model for adults was acceptable but not a good one. The model for children was found to be more reliable than the prediction model for adults.

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Unmasking Influenza Virus Infection in Patients Attended to in the Emergency Department

Cited by 39 publications

References 33 publications

Case-Control Study of Clinical Features of Influenza in Hospitalized Patients

Case-Control Study of Clinical Features of Influenza in Hospitalized Patients

Is Influenza an Influenza-Like Illness? Clinical Presentation of Influenza in Hospitalized Patients

Differences in clinical predictors of influenza in adults and children with influenza-like illness

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