Unmasking of Brugada syndrome in a patient with Coronavirus disease 2019 (COVID-19)

Guragai, Nirmal; Posimreddy, Sahitya; Vasudev, Rahul; Bhandari, Pragya; Elkatawy, Sherif; Pullatt, Raja; Shamoon, Fayez

doi:10.1080/00015385.2020.1761583

Cited by 3 publications

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“…6 Multiple potential triggers have been described including febrile illness, hypothermia, alcohol, medication, electrolyte derangements such as hypokalemia, autonomic changes, and cocaine abuse. 7,8 Patients often present with repeated episodes of syncope and in some cases, resuscitated SCD. Additionally, Brugada syndrome has a higher incidence of supraventricular tachyarrhythmias, including atrial and atrioventricular reentrant tachycardia and rarely monomorphic ventricular tachycardia.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“… 1 , 7 Patients with suspected Brugada syndrome must be evaluated for implantable cardioverter defibrillator (ICD) placement as this is the only effective prevention of SCD. 4 , 8 Quinidine and phosphodiesterase 3 inhibitors among other pharmacological treatments are also being used to manage Brugada syndrome. 4 Furthermore, radiofrequency ablation of ventricular ectopy was postulated as a therapeutic approach in patients with Brugada syndrome.…”

Section: Discussionmentioning

confidence: 99%

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A Case of STEMI Masquerading Brugada Syndrome: Emphasizing the Importance of Clinical Decision Making in Emergencies

Guragai

Vasudev

Shah

et al. 2021

Journal of Investigative Medicine High Impact Case Reports

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Brugada syndrome is a rare arrhythmogenic syndrome that is associated with an increased risk of ventricular fibrillation and sudden cardiac death. Electrocardiographic findings include patterns similar to a right bundle branch block (RBBB) and persistent ST-segment elevation in precordial leads (V1 and V2). There are numerous reports of Brugada syndrome mimicking ST-segment elevation myocardial infraction (STEMI); however, we describe a case of 47-year-old male who presented with STEMI mimics Brugada syndrome with preexisting RBBB. The patient developed polymorphic ventricular tachycardia generating into ventricular fibrillation right before catheterization making the diagnosis more challenging. The patient, eventually, was found to have obstructive coronary artery disease and no evidence of abnormal sodium channelopathy on further testing. This case highlights the importance of meticulous history taking and appropriate diagnostic test in establishing proper diagnosis of STEMI in a patient with preexisting RBBB, which can mimic Brugada syndrome.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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A Case of STEMI Masquerading Brugada Syndrome: Emphasizing the Importance of Clinical Decision Making in Emergencies

Guragai

Vasudev

Shah

et al. 2021

Journal of Investigative Medicine High Impact Case Reports

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“…It is also vital to properly differentiate COVID-19 symptoms from symptoms of cardiovascular diseases. Chang et al and Guragai et al both reported cases of previously unrecognized Brugada syndrome in COVID-19 patients presenting with fever [ 7 , 8 ]. Close monitoring of COVID-19 patients has also been highly encouraged because they are prone to several cardiovascular complications such as arrythmias, myocardial infarction, and stroke.…”

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confidence: 99%

The impact of COVID-19 on cardiology departments

Ramphul

Lohana²,

Verma³

et al. 2021

Arch Med Sci Atheroscler Dis

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The spread of the Coronavirus disease 2019 (COVID-19) pandemic throughout the world has persisted for over a year now [1]. Multiple hospitals in several countries do not have any free beds available and the health care providers are facing burn-out and fatigue. Some hospital centres such as in Lombardy, Italy even became an epicentre of infections [2]. We sought to briefly describe the changes seen and reported in literature by several cardiology departments from various regions across the world.

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The Cove in Coronavirus Disease 2019

Jordan Deles,

Mendoza,

Lim Ramirez

2022

International Journal of Heart Rhythm

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Brugada pattern is characterized by coved ST-segment elevation found in more than one of the precordial leads V1 through V3. In the emergence of coronavirus disease 2019 (COVID-19) pandemic, transient occurrence of these patterns is rarely observed in patients with severe acute respiratory syndrome coronavirus 2 infections. Whether these electrocardiographic findings develop due to fever or a direct effect of the infection itself is a matter that deserves further investigation. We present a young female and an elderly male with Brugada patterns on electrocardiograms when febrile due to COVID-19. After defervescence, these patterns disappeared and both patients progressively improved. We found nine similar articles, all involving male patients. Thus, our case of the young female patient may be the first reported case. It is worth noting that fever was not entirely simultaneous with the appearance of Brugada patterns in the other reports suggesting the possibility that COVID-19 itself with its unique pathogenic mechanism could directly underlie these electrocardiographic abnormalities.

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Unmasking of Brugada syndrome in a patient with Coronavirus disease 2019 (COVID-19)

Cited by 3 publications

References 0 publications

A Case of STEMI Masquerading Brugada Syndrome: Emphasizing the Importance of Clinical Decision Making in Emergencies

A Case of STEMI Masquerading Brugada Syndrome: Emphasizing the Importance of Clinical Decision Making in Emergencies

The impact of COVID-19 on cardiology departments

The Cove in Coronavirus Disease 2019

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