The number of refugees has increased exponentially due to international crises, wars, and political pressures in recent years worldwide. Turkey hosts the largest refugee population in the world with 3,672,646 Syrian refugees. This study aimed to examine the relationship among refugeesâ stress, life satisfaction, social support, coronavirus anxiety, and social aids they get during the COVID-19 process. We hypothesized that stress, social aids, and coronavirus anxiety could play a role in the relationship between life satisfaction, stress, and social support. A cross-sectional survey was used to collect data from 628 Syrian refugees via an online questionnaire in Turkey. Confirmatory factor, correlation, and multiple regression analyses were conducted. In addition, the moderator and mediator role of variables tested using the 95% bias-corrected confidence interval from 5000 resamples was generated by the bias-corrected bootstrapping method. The study results show that stress partially mediated the relationship between family support and life satisfaction and between friend support and life satisfaction. In addition, coronavirus anxiety had a moderating effect on the relationship between family support and stress and friend support and stress. Finally, social aids moderated the relationship between stress and life satisfaction. In conclusion, the role of social aids, stress, and coronavirus anxiety in the relationship between social support, stress, and life satisfaction has been revealed.