Heatwaves pose significant threats to socioeconomic and environmental systems, with their intensity and frequency expected to increase due to climate change. Despite their critical impacts, future heatwaves in Brazil remain underexplored, especially from a human-perceived perspective, which is crucial for assessing potential public health impacts. Here, we propose a method to assess heatwaves using the humidex (H) – a climate index that combines temperature and relative humidity to indicate human-perceived heat - alongside traditional temperature-based measures. Using bias-corrected simulations from 10 CMIP6 models under SSP2-4.5 and SSP5-8.5 scenarios, we quantified projected changes in heatwaves across Brazil. The results indicate that heatwaves will become more severe and prolonged, with greater changes under the SSP5-8.5 scenario by the end of the century, particularly in the North, Northeast, and Central regions. The magnitude of human-perceived heatwaves is expected to rise faster than temperature-based ones, underscoring the need for public health-focused assessments. CMIP6 models strongly agree on increased future heatwaves, potentially tripling population exposure in most Brazilian states, with the Southeast experiencing greater changes due to its larger population. These events are expected not only to affect more people but also to be more severe, exceeding over 60 days per year of serious danger (H > 45°C) by the end of the century under SSP5-8.5. Record-shattering events in the historical period are projected to become the norm by mid-century, highlighting the accelerating nature of these extreme events. Our findings emphasize the importance of considering human-perceived heat in climate impact studies and public health planning to mitigate potential impacts.