2023
DOI: 10.1161/jaha.123.030943
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Unraveling Potential Sex‐Specific Effects of Cardiovascular Medications on Longevity Using Mendelian Randomization

Man Ki Kwok,
C. Mary Schooling

Abstract: Background Establishing the sex‐specific efficacy of cardiovascular medications is pivotal to evidence‐based clinical practice, potentially closing the gender gap in longevity. Trials large enough to establish sex differences are unavailable. This study evaluated sex‐specific effects of commonly prescribed cardiovascular medications on lifespan. Methods and Results In a two‐sample Mendelian randomization study, established genetic variant… Show more

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