Unraveling the Relationship between the Concentrations of Hydrophobic Organic Contaminants in Freshwater Fish of Different Trophic Levels and Water Using Passive Sampling

Smedes, Foppe; Sobotka, Jaromír; Rusina, Tatsiana P.; Fialová, Pavla; Carlsson, Pernilla; Kopp, Radovan; Vrana, Branislav

doi:10.1021/acs.est.9b07821

Cited by 17 publications

(22 citation statements)

References 48 publications

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“…(B) Correlation of log K lipid/water with log K ow (line: log K lipid/water = 0.94 log K ow + 0.90, r 2 = 0.914) and of log K lipid/PDMS with log K ow (line: log K lipid/PDMS = 0.13 log K ow + 0.53, r 2 = 0.35). (C) log K lipid/water of the pork adipose tissue in comparison with log K lipid/water from the literature (mean of diverse oils, corn oil, fish oil, , and fish) and predictions using the LSER from Geisler et al…”

Section: Resultsmentioning

confidence: 99%

“…This issue can be overcome by multiple manual relocations of the silicone to assure that a fresh tissue is constantly in contact with the sampler. , However, this bears the risk of sample contamination and involves time-intensive laboratory logistics. Rolling thin PDMS sheets in jars together with tissue cubes or homogenates is an alternative sampling method for lean fish tissues. , …”

Section: Introductionmentioning

confidence: 99%

“…Rolling thin PDMS sheets in jars together with tissue cubes or homogenates is an alternative sampling method for lean fish tissues. 27,29 PDMS extracts can be subjected without extensive cleanup to instrumental analysis 30 and bioanalytical screening 21,23,26 because only small amounts of unwanted matrices are coextracted. Especially in toxicological screening studies using cell-based in vitro bioassays, conserving the original mixture composition is important because the losses of analytes during cleanup stages cannot be corrected with recovery standards and extensive extraction and cleanup procedures might cause contamination and blank effects.…”

Section: ■ Introductionmentioning

confidence: 99%

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Kinetics of Equilibrium Passive Sampling of Organic Chemicals with Polymers in Diverse Mammalian Tissues

Baumer

Jäsch

Ulrich

et al. 2021

Environ. Sci. Technol.

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Equilibrium passive sampling employing polydimethylsiloxane (PDMS) as a sampling phase can be used for the extraction of complex mixtures of organic chemicals from lipid-rich biota. We extended the method to lean tissues and more hydrophilic chemicals by implementing a mass-balance model for partitioning between lipids, proteins, and water in tissues and by accelerating uptake kinetics with a custom-built stirrer that effectively decreased time to equilibrium to less than 8 days even for a homogenized liver tissue with an only 4% lipid content. The partition constants log K lipid/PDMS between tissues and PDMS were derived from measured concentration in PDMS and the mass-balance model and were very similar for 40 neutral chemicals with octanol–water partition constants 1.4 < log K ow < 8.7, that is, log K lipid/PDMS of 1.26 (95% CI, 1.13–1.39) for the adipose tissue, 1.16 (1.00–1.33) for the liver, and 0.58 (0.42–0.73) for the brain. This conversion factor can be applied to interpret chemical analysis and in vitro bioassays after additionally accounting for a small fraction of coextracted lipids of <0.7% of the PDMS weight. PDMS is more widely applicable for passive sampling of mammalian tissues than previously thought, both, in terms of diversity of chemicals and the range of lipid contents of tissues and, therefore, an ideal method for human biomonitoring to be combined with in vitro bioassays.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: ■ Introductionmentioning

confidence: 99%

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Kinetics of Equilibrium Passive Sampling of Organic Chemicals with Polymers in Diverse Mammalian Tissues

Baumer

Jäsch

Ulrich

et al. 2021

Environ. Sci. Technol.

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“…This divergence in activity ratios has been shown for PCBs in freshwater fish but not for marine fish and has been attributed to the slow kinetics of transfer of these chemicals from water to organisms at the base of trophic food chains. 9 Past experiments to assess the bioaccumulation of PCBs in cod exposed to sediment/organisms from Oslofjord demonstrated generally low accumulation rates. 43 It may be that temperature and low feeding rates may play a role here.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

Passive Sampling Helps the Appraisal of Contaminant Bioaccumulation in Norwegian Fish Used for Regulatory Chemical Monitoring

Allan

Vrana

Ruus

2022

Environ. Sci. Technol.

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Hexachlorobenzene (HCB), listed on the Stockholm Convention on persistent organic pollutants and regulated as a hazardous priority pollutant by the Water Framework Directive (WFD), is ubiquitously distributed in the environment and assumed to mildly biomagnify in aquatic foodwebs. The proposal to include trophic magnification factors (TMFs) in the procedure for comparing contaminant levels in biota at different trophic levels (TLs) with WFD environmental quality standards requires adequate selection of TMFs. In the first step of our study, we compared two independently obtained datasets of pentachlorobenzene (PeCB) and HCB concentration ratios from passive sampling (PS) in water and in fish through routine monitoring programs in Norway to evaluate possible biomagnification. In this procedure, PeCB is used for benchmarking the bioconcentration in fish, and the observed HCB/PeCB ratios in fish are compared with ratios expected in the case of (i) HCB bioconcentration or (ii) biomagnification using published TMF values. Results demonstrate that it is not possible to confirm that HCB biomagnifies in fish species that would be used for WFD monitoring in Norway and challenges the proposed monitoring procedures for such compounds in Norwegian or European waters. In the second step, fish-water chemical activity ratios for HCB and PeCB as well as for polychlorinated biphenyls where biota and PS were conducted alongside were calculated and found to rarely exceed unity for cod (Gadus morhua), a fish species with a TL of approximately 4.

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“…PSDs have shown the potential to express the thermodynamic status of HOC partitioning between the environment and the lipid tissue of organisms [ 14 , 15 , 17 , 19 ]. A suitable measure can be the C Lip / C Lip⇆Medium ratio, also referred to as the partitioning status of lipids in organisms relative to their environment.…”

Section: Introductionmentioning

confidence: 99%

Exploring the partitioning of hydrophobic organic compounds between water, suspended particulate matter and diverse fish species in a German river ecosystem

et al. 2022

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Background Bioaccumulation of hydrophobic organic compounds (HOCs) along freshwater food chains is a major environmental concern as top predators in food webs are relevant for human consumption. To characterize and manage the associated risks, considerable numbers of organisms are sampled regularly for monitoring purposes. However, ethical and financial issues call for an alternative, more generic and more robust approach for assessing the internal exposure of fish that circumvents large variability in biota sampling due to interindividual differences. Passive sampling devices (PSDs) offer a fugacity-based approach for pollutant enrichment from different abiotic environmental compartments with a subsequent estimation of bioaccumulation in fish which we explored and compared to HOC concentrations in fish as determined using traditional approaches. Results In this study, concentrations in silicone-based PSDs applied to the water phase and suspended particulate matter (SPM) of a river polluted with HOCs were used to estimate the concentration in model lipids at thermodynamic equilibrium with either environmental compartment. For comparison, muscle tissue of seven fish species (trophic level 1.8 to 2.8) was extracted using traditional exhaustive solvent extraction, and the lipid-normalized concentrations of HOCs were determined. The PSD-based data from SPM proved to be a more conservative estimator for HOCs accumulated in fish than those from water. Body length of the fish was found to be more suitable to describe increasing accumulation of HOCs than their trophic level as derived from stable isotope analysis and might offer a suitable alternative for future studies. Conclusions By combining fugacity-based sampling in the abiotic environment, translation into corresponding concentrations in model lipids and body length as an indicator for increasing bioaccumulation in fish, we present a suggestion for a robust approach that may be a meaningful addition to conventional monitoring methods. This approach potentially increases the efficiency of existing monitoring programs without the need to regularly sacrifice vertebrate species. Graphical Abstract

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Unraveling the Relationship between the Concentrations of Hydrophobic Organic Contaminants in Freshwater Fish of Different Trophic Levels and Water Using Passive Sampling

Cited by 17 publications

References 48 publications

Kinetics of Equilibrium Passive Sampling of Organic Chemicals with Polymers in Diverse Mammalian Tissues

Kinetics of Equilibrium Passive Sampling of Organic Chemicals with Polymers in Diverse Mammalian Tissues

Passive Sampling Helps the Appraisal of Contaminant Bioaccumulation in Norwegian Fish Used for Regulatory Chemical Monitoring

Exploring the partitioning of hydrophobic organic compounds between water, suspended particulate matter and diverse fish species in a German river ecosystem

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