Unreliable feedback deteriorates information processing in primary visual cortex

Varrier, Rekha S.; Rothkirch, Marcus; Stuke, Heiner; Guggenmos, Matthias; Sterzer, Philipp

doi:10.1016/j.neuroimage.2020.116701

Cited by 2 publications

(2 citation statements)

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“…Alternatively, the representation of the overall precision of the visual modality might be reduced by the presence of ambiguous visual targets, thereby ultimately downweighting the salience of visual information in learning and predictive processing (Friston, 2009). Indeed, unreliable feedback reduces accuracy and deteriorates representation of visual stimuli in the visual cortex (Varrier et al, 2020). Furthermore, we show that perceptual decisions are comparably influenced by expectations of multiple origin (see effect sizes in Table 1.).…”

Section: Discussionmentioning

confidence: 69%

“…visual cortex) is assumed to be implemented by gamma-band oscillations (Richter et al, 2017). As mentioned above (Friston, 2009), prior expectations have a stronger weight when sensory input is uncertain and at the neural level, increased frontal theta and fronto-parietal and occipital-parietal beta power have been observed when processing ambiguous stimuli (Maksimenko et al, 2020), while the precision of lower-level priors in the primary visual cortex was reduced if the environment was inconsistent (Varrier et al, 2020). Finally, lower-level priming effects cooccur with reductions in neural activity -termed 'repetition suppression' (Henson & Rugg, 2003) or 'expectation suppression ' (de Lange et al, 2018) -which may reflect top-down effects of expectations based on stimulus frequency statistics (Summerfield et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

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Cross-modal auditory priors drive the perception of bistable visual stimuli with reliable differences between individuals [preprint]

Pálffy¹,

Farkas²,

Csukly³

et al. 2021

Preprint

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Background: It is a widely held assumption that the brain performs perceptual inference by combining sensory information with prior expectations, all being weighted by their uncertainty. Perception of ambiguous stimuli is influenced by higher- and lower-level priors, which can be manipulated with associative learning and sensory priming, respectively. Here, we investigate the differential effect of auditory vs. visual associative cues on perception of illusory visual motion, and we also take lower-level priming effects into account. Furthermore, we examine the test-retest reliability of individual differences and their correlates. Methods: Healthy individuals (N=29; 13 men, mean (SD) age = 27.8 (9.6) years) performed a perceptual inference task (640 trials) twice with a one-week delay. They reported the perceived direction of (illusory) motion of dot pairs, which were preceded by a visuo-acoustic cue that probabilistically predicted the direction of the motion. In 30% of the trials, motion direction was ambiguous, and in half of these trials, the auditory vs. the visual cue predicted opposing directions. Cue-stimulus contingency could change every 40 trials. To explore the relationship with self-reported alterations in perception and thought, schizotypal traits were measured with the short Oxford–Liverpool Inventory of Feelings and Experiences questionnaire.Results: Importantly, on ambiguous trials where the visual and the auditory cue predicted conflicting directions of motion, participants made more decisions consistent with the prediction of the acoustic cue. Increased predictive processing under stimulus uncertainty was indicated by slower responses to ambiguous (vs. non-ambiguous) stimuli. Associative learning influenced perceptual decisions: we observed slower responses to less (vs. more) predictable non-ambiguous stimuli and an above-chance rate of cue-congruent decisions on ambiguous trials. Furthermore, priming effects were also observed in that perception of ambiguous stimuli was influenced by perceptual decisions on the previous ambiguous and unambiguous trials as well. Critically, all the above effects had substantial inter-individual variability which showed high test-retest reliability (intraclass correlation coefficient (ICC) > 0.78). Finally, indicators reflecting the dominance of associative learning vs. sensory priming (higher- vs. lower-level priors, respectively) clustered together, these sets of variables were inversely related to each other, and some task-derived indicators showed stable and meaningful associations with schizotypal traits .Discussion: Overall, higher-level priors based on auditory (as compared to visual) information seem to have greater influence on the perception of illusory visual motion, replicating the sensory conditioning effect. The influence of lower-level priors was evident as well, suggesting that sensory priming was also in action. Importantly, we observed large and stable differences in various aspects of task performance. Computational modelling combined with neuroimaging could allow testing hypotheses regarding the potential mechanisms causing these behavioral effects (e.g. characteristics of visual vs. auditory processing, perceptual organisation and attention, and uncertainty). The reliability of the behavioural differences implicates that such perceptual inference tasks could be valuable tools during large-scale biomarker and neuroimaging studies.

show abstract

Section: Discussionmentioning

confidence: 69%

Section: Introductionmentioning

confidence: 99%

Cross-modal auditory priors drive the perception of bistable visual stimuli with reliable differences between individuals [preprint]

Pálffy¹,

Farkas²,

Csukly³

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

Cross-modal auditory priors drive the perception of bistable visual stimuli with reliable differences between individuals

Pálffy

Farkas

Csukly

et al. 2021

Sci Rep

View full text Add to dashboard Cite

It is a widely held assumption that the brain performs perceptual inference by combining sensory information with prior expectations, weighted by their uncertainty. A distinction can be made between higher- and lower-level priors, which can be manipulated with associative learning and sensory priming, respectively. Here, we simultaneously investigate priming and the differential effect of auditory vs. visual associative cues on visual perception, and we also examine the reliability of individual differences. Healthy individuals (N = 29) performed a perceptual inference task twice with a one-week delay. They reported the perceived direction of motion of dot pairs, which were preceded by a probabilistic visuo-acoustic cue. In 30% of the trials, motion direction was ambiguous, and in half of these trials, the auditory versus the visual cue predicted opposing directions. Cue-stimulus contingency could change every 40 trials. On ambiguous trials where the visual and the auditory cue predicted conflicting directions of motion, participants made more decisions consistent with the prediction of the acoustic cue. Increased predictive processing under stimulus uncertainty was indicated by slower responses to ambiguous (vs. non-ambiguous) stimuli. Furthermore, priming effects were also observed in that perception of ambiguous stimuli was influenced by perceptual decisions on the previous ambiguous and unambiguous trials as well. Critically, behavioural effects had substantial inter-individual variability which showed high test–retest reliability (intraclass correlation coefficient (ICC) > 0.78). Overall, higher-level priors based on auditory (vs. visual) information had greater influence on visual perception, and lower-level priors were also in action. Importantly, we observed large and stable differences in various aspects of task performance. Computational modelling combined with neuroimaging could allow testing hypotheses regarding the potential mechanisms causing these behavioral effects. The reliability of the behavioural differences implicates that such perceptual inference tasks could be valuable tools during large-scale biomarker and neuroimaging studies.

show abstract

Unreliable feedback deteriorates information processing in primary visual cortex

Cited by 2 publications

References 38 publications

Cross-modal auditory priors drive the perception of bistable visual stimuli with reliable differences between individuals [preprint]

Cross-modal auditory priors drive the perception of bistable visual stimuli with reliable differences between individuals [preprint]

Cross-modal auditory priors drive the perception of bistable visual stimuli with reliable differences between individuals

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