Unrevealing the therapeutic potential of artesunate against emerging zoonotic Babesia microti infection in the murine model
Saqib Ali Fazilani,
Wei An,
Sihong Li
et al.
Abstract:Babesiosis, a zoonotic blood protozoal disease, threatens humans and animals and is difficult to treat due to growing antimicrobial resistance. The study aimed to investigate the therapeutic efficacy of artesunate (AS), a well-known derivative of artemisinin, against Babesia microti (B. microti) using a murine infection model. Male BALB/c mice (6 weeks old; 15 per group) were chosen and randomly divided into 1) the control group, 2) the B. microti group, and 3) the B. microti + artesunate treatment groups. AS … Show more
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