In industrial piping systems, turbomachinery, heat exchangers etc., pipe bends are essential components. Computational fluid dynamics (CFD), which is frequently used to analyse the flow behaviour in such systems, provides extremely precise estimates but is computationally expensive. As a result, a computationally efficient method is developed in this paper by leveraging machine learning for such computationally expensive CFD problems. Random forest regression (RFR) is used as the machine learning algorithm in this work. Four different fluid flow characteristics (i.e., axial velocity, x-velocity, y-velocity and z-velocity) are studied in this work. The accuracy of the RFR models is assessed by using a number of statistical metrics such as mean-absolute error (MAE), mean-squared-error (MSE), root-mean-squared-error (RMSE), maximum error (Max.Error) and median error (Med.Error) etc. It is observed that the RFR models can produce considerable cost reductions in computing by surrogating the CFD model. Minor loss in estimation accuracy as compared to the CFD models is observed. While the magnitude of intricate flow characteristics such as the additional vortices are correctly predicted, some error in their location is observed.