Study of heat and mass transfers is carried out for MHD Oldroyd-B fluid (OBF) over an infinite vertical plate having time-dependent velocity and with ramped wall temperature and constant concentration. It is proven in many already published articles that the heat and mass transfers do not really or always follow the classical mechanics process that is known as memoryless process. Therefore, the model using classical differentiation based on the rate of change cannot really replicate such dynamical process very accurately, thus, a different concept of differentiation is needed to capture such process. Very recently, a new class of differential operators were introduced and have been recognized to be efficient in capturing processes following the power-law, the decay law and the crossover behaviors. For the study of heat and mass transfers, we applied the newly introduced differential operators to model such flow and compare the results with integer-order derivative. Laplace transform and inversion algorithms are used for all the cases to find analytical solutions and to predict the influences of different parameters. The obtained analytical solutions were plotted for different values of fractional orders [Formula: see text] and [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text] and [Formula: see text] on the velocity field. In comparison, Atangana–Baleanu (ABC) fractional derivatives are found to be the best to explain the memory effects than the classical, Caputo (C) and Caputo–Fabrizio (CF) fractional derivatives. Some calculated values for Nusselt number and Sherwood number are presented in tables. Moreover, from the present solutions, the already published results were found as limiting cases.