The objective of the paper is to demonstrate the importance of the unsteady Computational Fluid Dynamics (CFD) simulations and long-term measurements for the reliable assessment of thermal comfort indoors, for proper categorization of the indoor thermal environment and for identifying the reasons for complaints due to draught discomfort. Numerical simulations and experimental measurements were applied in combination to study ventilation in a field laboratory, a university classroom with a controlled indoor environment. Strong unsteadiness of the airflow was registered both in the unsteady RANS results and the real-scale long-term velocity data measured with thermo anemometer. Low-frequency high-amplitude velocity fluctuations observed lead to substantial time variation of the draught rate. In case of categorization of a thermal environment, the point measurements or steady-state RANS computations would lead to wrong conclusions as well as they cannot be used for identification of the reasons for people’s complaints due to draught discomfort if strong unsteadiness of the airflow exists. It is demonstrated that the length of the time interval for draught rate (DR) assessment may not be universal if low-frequency high-amplitude pulsations are present in the room airflow.