2019
DOI: 10.1101/845537
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Unsupervised domain adaptation for the automated segmentation of neuroanatomy in MRI: a deep learning approach

Abstract: Neuroanatomical segmentation in T1-weighted magnetic resonance imaging of the brain is a prerequisite for quantitative morphological measurements, as well as an essential element in general preprocessing pipelines. While recent fully automated segmentation methods based on convolutional neural networks have shown great potential, these methods nonetheless suffer from severe performance degradation when there are mismatches between training (source) and testing (target) domains (e.g. due to different scanner ac… Show more

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Cited by 4 publications
(3 citation statements)
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“…To this end, fine-tuning the freelyavailable learned model onto any new MR unit will likely be necessary (32). Unsupervised domain adaptation techniques may be an alternative approach allowing to implement our model onto a new image domain without the need for paired sets (33). Second, patients imaged in the intermediate known onset time window (i.e., 4.5-12h) were underrepresented (namely, 10% of all patients imaged within 12h), as in previous studies (29,34).…”
Section: Discussionmentioning
confidence: 99%
“…To this end, fine-tuning the freelyavailable learned model onto any new MR unit will likely be necessary (32). Unsupervised domain adaptation techniques may be an alternative approach allowing to implement our model onto a new image domain without the need for paired sets (33). Second, patients imaged in the intermediate known onset time window (i.e., 4.5-12h) were underrepresented (namely, 10% of all patients imaged within 12h), as in previous studies (29,34).…”
Section: Discussionmentioning
confidence: 99%
“…DASiS solutions have been designed for MRI segmentation of liver and kidney (Valindria et al, 2018), neuroanatomy (Novosad et al, 2019), retinal vessel (Huang et al, 2020b), white matter hyper-intensities (Orbes-Arteaga et al, 2019), and multiple sclerosis lesions (Ackaouy et al, 2020). Furthermore, Bermúdez-Chacón et al (2018) apply DASiS to microscopic image segmentation; Dou et al (2018) and Jiang et al (2018) perform adaptation between CT and MRI images for cardiac structure segmentation and for lung cancer segmentation, respectively.…”
Section: Medical Image Segmentationmentioning
confidence: 99%
“…UDA can be used for multi-site segmentation of MS lesions from MRI (Ackaouy et al 2020). Furthermore, extensive data augmentation of MR images has been shown to improve segmentation results (Novosad, Fonov, and Collins 2019;Billot et al 2020). Another UDA approach, based on domainadversarial neural networks (Ganin et al 2016), is used for multi-site brain lesion segmentation (Kamnitsas et al 2017).…”
Section: Related Workmentioning
confidence: 99%