2024
DOI: 10.21037/tp-23-546
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Untargeted lipidomics of bronchopulmonary dysplasia induced by hyperoxia exposure in rats

Yubai Li,
Qian Su,
Xudong Yan
et al.

Abstract: Background Bronchopulmonary dysplasia (BPD), characterized by impaired lung development, remains a leading cause of morbidity and mortality in premature infants. The synthesis and metabolism of lipids play a critical role in normal lung development, such as dipalmitoylphosphatidylcholine, a key component of pulmonary surfactant (PS). Therefore, we conducted a lipidomics study of rat lung tissue to explore the changes of pulmonary lipid composition in the progression of BPD disease. … Show more

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