Untargeted metabolomics analysis of non-volatile metabolites and dynamic changes of antioxidant capacity in Douchi with edible mushroom by-products

Rong, Pei-Xiu; He, Xiao-Qin; Ayyash, Mutamed; Liu, Yi; Wu, Ding‐Tao; Geng, Fang; Li, Hua-Bin; Ng, Brian W.-H.; Liu, Hongyan; Gan, Ren‐You

doi:10.1016/j.foodchem.2023.137066

Cited by 12 publications

(1 citation statement)

References 39 publications

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“…The fungi within these mushrooms produce unique bioactive compounds [7][8][9], with derived compounds also fulfilling nutritional roles [10]. These compounds not only serve as food sources, but also hold potential as biopharmaceuticals [11], earning them the designation of "drug alternatives".…”

Section: Introductionmentioning

confidence: 99%

Isolation and Identification of Chemical Compounds from Agaricus blazei Murrill and Their In Vitro Antifungal Activities

Yu,

Li,

et al. 2023

Molecules

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This study explores the antifungal properties of Agaricus blazei Murrill, a valuable medicinal and edible fungus. Six compounds (1–6) were first isolated from A. blazei using various isolation techniques and identified using spectroscopic methods. These compounds include linoleic acid, 1,1’-oxybis(2,4-di-tert-butylbenzene), glycerol monolinoleate, volemolide (17R)-17-methylincisterol, (24s)-ergosta-7-en-3-ol, and dibutyl phthalate. This study also assesses the antifungal activities of these compounds against Trichophyton mentagrophology, Trichophyton rubrum, Candida albicans, and Cryptococcus neoformans. The results demonstrate varied sensitivities against these pathogenic fungi, with compound 2 showing significant inhibition against T. mentagrophology, compound 3 showing significant inhibition against T. rubrum, and compound 6 showing significant inhibition against C. albicans. This study underscores the medicinal potential of A. blazei as an antifungal agent and sheds light on its valuable research implications.

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