Untersuchungen �ber die Rindenpotentiale nach Reizung des Nucleus caudatus bei der Katze

Electrical Signs of the Relation between Caudate Nucleus and Cerebral Cortex in Cats1

“…1954), there is no anatomical evidence of direct caudate-cortical connections (Vo-NEIDA 1960) nor were such connections found by strychnine neuronography (DUSSER DE BARENNE and MCCULLOCH 1938). It has been reported that cortical spindle bursts may be elicited by stimulation of the head of the caudate in cat ( JUNG and TONNIES 1950, SHIMAMOTO and VERZEANO 1954, UMBACH 1959, WIECK et al 1960. This response was abolished by destruction of the diffuse thalamic projection system (SHIMAMOTO and VERZEANO 1954), a finding consistent with the anatomical evidence (RANSON, RANSON and RANSON 1941, PAPEZ 1942, WOODBURNE, CROSBY and MCCOTTER 1946, GLEES 1945, JOHNSON and CLEMENTE 1959 if the nucleus ventralis anterior and lateralis were included in the lesion.…”

“…ii) The negative results were confirmed using a bipolar stimulating electrode of small diameter and conventional design. Spread of current from the commonly used concentric electrodes were thought to explain the results reported by other authors (AJMONE- MARSAN and DILWORTH 1953, STOUPEL and TERZUOLO 1954, PURPURA, HAUSE-PIAN and GRUNDFEST 1958, WIECK et al 1960).…”

“…This response was abolished by destruction of the diffuse thalamic projection system (SHIMAMOTO and VERZEANO 1954), a finding consistent with the anatomical evidence (RANSON, RANSON and RANSON 1941, PAPEZ 1942, WOODBURNE, CROSBY and MCCOTTER 1946, GLEES 1945, JOHNSON and CLEMENTE 1959 if the nucleus ventralis anterior and lateralis were included in the lesion. Cortical recruiting responses (DEMPSEY and MORISON 1942) were found to be elicited from the head of the caudate (AJMONE- MARSAN and DILWORTH 1953, STOUPEL and TERZUOLO 1954, WIECK et al 1960 but in this case too, a direct caudate-cortical pathway seemed to be excluded. When cortical seizure activity was inhibited by single shocks to the caudate (UM-BACH 1959) the effect was thought to be mediated by the intralaminar thalamic nuclei.…”

Kritische Stellungnahme zum Begriff der Neuroleptika

“…Die Hemmung der elektrographischen Weckreaktion korreliert bei den klassischen (18,23). In den ersten 200 msec nach dem Reiz im N. caudatus tritt eine nicht immer konstante Folge von Potentialen negativer und positiver Polarität auf; mit einer Gesamtlatenz von 200 bis 300 msec folgt dann die typische Kaudatumspindel, eine Gruppe von Potentialen mit einer Frequenz von 8 bis 12/sec, deren Amplitude crescendo-und descrescendoartig zu-und abnimmt (25,26,27). Ihre Dauer beträgt normalerweise bis zu 1 sec, ist aber sehr wechselnd und kann gelegentlich auch sehr viel höhere Werte erreichen.…”