Untreated sleep apnea syndrome and glycemic control in patients with type 2 diabetes

Response to Kawada: Untreated sleep apnea syndrome and glycemic control in patients with type 2 diabetes

“…We agree with Dr Kawada's comments on the sample size and its effect on the regression analysis, as well as with his observation on psychological factors that may have affected glycemic control . To add to this, sleep duration and sleep quality may also have affected the glycemic control of the patients enrolled in our study.…”

“…Dr Kawada noted that in previous studies enrolling people without diabetes an association was observed between the severity of SAS and HbA1c, as well as between nocturnal hypoxemia and the risk of poor glycemic control . Studies in patients with T2D had mixed results, with studies showing no relationship between SAS and glycemic control, an association between SAS severity as assessed by the apnea–hypopnea index and glycemic control, or an association between mean and minimum O 2 saturation and glycemic control .…”