Unusual Case of Wilson’s Disease and Coexisting Autoimmune Hepatitis

Simultaneous Presentation of Autoimmune Hepatitis and Wilson's Disease: A Systematic Review Study

“…Out of 10 studies, there were 8 case reports [7,9,10,18,[20][21][22][23], 1 opinion study [24], and 1 letter to the editor [25]. So that 6 case report studies, 1 opinion study, and the letter to the editor reported one case [9, 10,18,20,[22][23][24]. The other two studies reported two [21], and four cases [7], respectively.…”

“…Eight (57%) out of 14 participants were female. Diagnosis direction was autoimmune hepatitis to Wilson disease in 8 cases [7,9,21,23,24], and reverse in 3 cases [7,20,22]. In three cases [10,18,25], the simultaneity of Wilson disease and autoimmune hepatitis was considered from the beginning with no primary and secondary diagnosis.…”

“…In three cases [10,18,25], the simultaneity of Wilson disease and autoimmune hepatitis was considered from the beginning with no primary and secondary diagnosis. Finally, out of 8 patients [7,15,21,23,24] diagnosed with autoimmune hepatitis to Wilson disease, in two cases [9, 23], the primary diagnosis of autoimmune hepatitis was rejected.…”

“…In another case [24], the primary diagnosis of autoimmune hepatitis was not rejected and remained. In three cases [7,20,22] with the diagnosis of Wilson disease to autoimmune hepatitis, in one case [22] primary diagnosis of Wilson disease was rejected.…”

“…It should be noted that in other studies, no explanation was given regarding rejection or non-rejection of primary diagnosis. The duration from primary diagnosis to secondary diagnosis varied from one month to three years [7,9,20,21,24], although in some studies, this time has not been reported [22,23].…”