Unusual clinical presentations of gout

Abstract

Although classic gout is still most commonly seen, the disease can manifest as with a wide array of presentations. It is likely that such atypical presentations are a result of a complexity of reasons. When presented with a diagnostic challenge in a patient with gout, the clinician should be aware of unusual manifestations of gout and consider it in the differential.

CARD8 rs2043211 Polymorphism is Associated with Gout in a Chinese Male Population

“…The clinical feature of gout is recurrent episodes of acute gouty arthritis, which can present as tophi, joint deformity, urinary lithiasis and other chronic symptoms [1,2]. Recently, with development of the economy and dietary changes, the prevalence and incidence of gout have risen rapidly [3,4].…”

Pancreatic gout and the role of multimodality imaging in its management

“…Gouty tophi are known to have a wide range of unusual localisation in the body 3 4. There are only two case reports of pancreatic gout prior to our case, one mimicked pancreatic neoplasm and the other mimicked infection of a pancreatic pseudocyst 1 2.…”

“…Gouty tophi are also known to deposit in malignant tumours elsewhere in the body 3 4. Confident diagnosis of pancreatic gout is thus best achieved by excluding malignancy through tissue sampling and follow-up for complete resolution.…”

Tophaceous Gout Involving the Whole Spine: An Unusual Case Report

“…Gout is most common in the feet. In cases of patients with spinal gout, many present with symptomatic cord or root compression (1)(2)(3)(4). In most of these patients, spinal involvement is secondary to involvement of the appendicular skeleton (2).…”