Unusual Complication of Aortic Valve Grape-Like Myxoma

Aortic Valve Myxoma Presenting with a Stroke: A case report and review of the literature

“…[4][5][6][7][8][9][10][11][12][13][14] Interestingly, nine of these previously reported patients were male, as in the current case; this is contrary to the usual female preponderance of myxoma cases. 1,[4][5][6][7][8][9]11,13,14 Overall, six aortic valve myxoma patients were symptomatic, with symptoms largely attributable to distal embolisation and ischaemia, including three cases with stroke, two with myocardial infarctions and one with limb ischaemia. 4,6,8,[11][12][13] Clinicians should therefore be aware of stroke as a potential presentation of aortic valve myxoma.…”

“…1,[4][5][6][7][8][9]11,13,14 Overall, six aortic valve myxoma patients were symptomatic, with symptoms largely attributable to distal embolisation and ischaemia, including three cases with stroke, two with myocardial infarctions and one with limb ischaemia. 4,6,8,[11][12][13] Clinicians should therefore be aware of stroke as a potential presentation of aortic valve myxoma.…”

Aortic valve myxoma at the extreme age: a review of literature

“…To the best of our knowledge, only nine cases of aortic myxoma have been reported in the literature (table 1). However, the patient in the present case is the oldest among these cases; the reported age of the cases of valvular myxoma ranged between 154 and 72 years 5…”

“…On clinical examination, one of the patients presented with embolic myocardial infarction,4 three patients had embolic stroke,6–8 one had embolic occlusion of the abdominal aorta, one patient demonstrated embolic occlusion of the common femoral artery9 and three patients exhibited an incidental finding on TTE 5 10 11. Furthermore, the myxoma was attached to the right coronary cusp in three patients,6 7 11 to the left coronary cusp in two patients (including the present case),10 and to the non-coronary cusp in two patients4 5; two patients exhibited fusion of the left and right coronary cusps 8 9. Valvular myxomas tend to have a smaller cellular component, fewer giant cells and less perivascular cuffing of tumour cells 12…”

“…The efficacy of surgical resection with clear margins, while preserving the valve architecture4 10 and valve repair or replacement,9–11 is dependent on the size of the tumour, in order to prevent recurrence. In cases without complex myxoma syndrome, recurrence of tumour is rare if the resection is appropriately performed 13.…”